3,5-Bis[[(tert-Butyl)diMethylsilyl]oxy]benzeneMethanol

Base Information

• Chemical Name: 3,5-Bis[[(tert-Butyl)diMethylsilyl]oxy]benzeneMethanol
• CAS No.: 103929-84-6
• Molecular Formula: C19H36O3Si2
• Molecular Weight: 368.664
• Mol file: 103929-84-6.mol

Synonyms:3,5-Bis[[(tert-Butyl)dimethylsilyl]oxy]benzenemethanol;

Chemical Property of 3,5-Bis[[(tert-Butyl)diMethylsilyl]oxy]benzeneMethanol

Chemical Property:

• PSA: 38.69000
• LogP: 5.94690
• Solubility.: Ethyl Acetate, Hexanes

Purity/Quality:

98%min ^*data from raw suppliers

3,5-Bis[[(tert-Butyl)dimethylsilyl]oxy]benzenemethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3,5-Bis[[(tert-Butyl)dimethylsilyl]oxy]benzenemethanol is a reactant used in the synthesis of natural polyhydroxystilbenes.

Technology Process of 3,5-Bis[[(tert-Butyl)diMethylsilyl]oxy]benzeneMethanol

There total 10 articles about 3,5-Bis[[(tert-Butyl)diMethylsilyl]oxy]benzeneMethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl 3,5-bis(tert-butyldimethylsilyloxy)benzoate (103929-83-5) → [3,5-di(tert-butyldimethylsilanyloxy)phenyl]methanol (103929-84-6)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Ambient temperature;

DOI:10.1055/s-1998-2193

Reference yield: 98.0%

→ [3,5-di(tert-butyldimethylsilanyloxy)phenyl]methanol (103929-84-6)

Guidance literature:

Reference yield: 86.0%

3,5-bis(tert-butyldimethylsilyloxy)benzaldehyde (187803-40-3) → [3,5-di(tert-butyldimethylsilanyloxy)phenyl]methanol (103929-84-6)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.5h;

DOI:10.1021/acs.jnatprod.6b00861

upstream raw materials:

methyl 3,5-bis(tert-butyldimethylsilyloxy)benzoate

3,5-bis(tert-butyldimethylsilyloxy)benzoic acid tert-butyldimethylsilyl ester

1-carbomethoxy-3,5-dihydroxybenzene

tert-butyldimethylsilyl chloride

Downstream raw materials:

oxyresveratrol-2'-O-β-D-glucopyranoside

1,3-dihydroxy-5-vinylbenzene

5-vinyl-1,3-phenylene diacetate

piceatannol 3'-O-β-D-glucopyranoside