HO-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala-NH₂

Base Information

Chemical Name:HO-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala-NH₂
CAS No.:1610523-76-6
Molecular Formula:C₄₃H₅₉N₅O₇
Molecular Weight:757.971
Hs Code.:

HO-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala-NH<SUB>2</SUB>

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Suppliers and Price of HO-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala-NH₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of HO-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala-NH₂

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Technology Process of HO-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala-NH₂

There total 1 articles about HO-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala-NH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: Fmoc-Leu-preloaded Wang resin, deprotected

: 35661-60-0,126727-03-5,114360-54-2
N-(9-fluorenylmethoxycarbonyl)-D-leucine

: 103478-58-6,84000-11-3
Fmoc-N-methylvaline

: 189937-46-0,201484-50-6
Fmoc-3,3-diphenyl-D-alanine

: 201335-88-8
FMOC-(4-methoxy-D-phenylalanine)

: 1610523-76-6
HO-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala-NH₂

Guidance literature:: Fmoc-Leu-preloaded Wang resin, deprotected; Fmoc-N-methylvaline; With benzotriazol-1-ol; diisopropyl-carbodiimide; In N,N-dimethyl-formamide; 2-chlorotrityl-leucine resin

With piperidine; In N,N-dimethyl-formamide; isopropyl alcohol; for 0.433333h; 2-chlorotrityl-leucine resin

N-(9-fluorenylmethoxycarbonyl)-D-leucine; Fmoc-3,3-diphenyl-D-alanine; FMOC-(4-methoxy-D-phenylalanine); Further stages;
DOI:10.1021/ml500114p

Reference yield: 32.0%

: 1610523-76-6
HO-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala-NH₂

: 1610523-53-9
cyclo-Leu-N-Me-Val-D-Leu-D-Tyr(Me)-3,3-diphenyl-D-Ala

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; HATU; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In dichloromethane;
DOI:10.1021/ml500114p