1-(1-Chloroethyl-ethoxyphosphoryl)oxyethane

Base Information

• Chemical Name: 1-(1-Chloroethyl-ethoxyphosphoryl)oxyethane
• CAS No.: 10419-78-0
• Molecular Formula: C6H14ClO3P
• Molecular Weight: 200.602
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID101289377
• Nikkaji Number: J117.032E
• Mol file: 10419-78-0.mol

Synonyms:10419-78-0;diethyl 1-chloroethylphosphonate;(1-Chloroethyl)phosphonic acid diethyl ester;1-chloro-1-diethoxyphosphorylethane;1-(1-chloroethyl-ethoxyphosphoryl)oxyethane;SCHEMBL13613852;DTXSID101289377;Diethyl P-(1-chloroethyl)phosphonate

Chemical Property of 1-(1-Chloroethyl-ethoxyphosphoryl)oxyethane

Chemical Property:

• PSA: 45.34000
• LogP: 2.83730
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 200.0369090
• Heavy Atom Count: 11
• Complexity: 141

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOP(=O)(C(C)Cl)OCC

Technology Process of 1-(1-Chloroethyl-ethoxyphosphoryl)oxyethane

There total 2 articles about 1-(1-Chloroethyl-ethoxyphosphoryl)oxyethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

(1,1-dichloro-ethyl)-phosphonic acid diethyl ester (51346-81-7) → diethyl 1-chloroethylphosphonate (10419-78-0) + (E)-p-methoxyphenyl-2 methyl-1 epoxy-1,2 ethanephosphonate (123098-27-1,123098-28-2) + (Z)-p-methoxyphenyl-2 methyl-1 epoxy-1,2 ethanephosphonate (123098-27-1,123098-28-2)

Guidance literature:

With tetramethylammonium tetrafluoroborate; 4-methoxy-benzaldehyde; In N,N-dimethyl-formamide; Yields of byproduct given; Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag;

Reference yield: 6.0%

(1,1-dichloro-ethyl)-phosphonic acid diethyl ester (51346-81-7) + 4-methoxy-benzaldehyde (123-11-5) → diethyl 1-chloroethylphosphonate (10419-78-0) + (E)-p-methoxyphenyl-2 methyl-1 epoxy-1,2 ethanephosphonate (123098-27-1,123098-28-2) + (Z)-p-methoxyphenyl-2 methyl-1 epoxy-1,2 ethanephosphonate (123098-27-1,123098-28-2)

Guidance literature:

With tetramethylammonium tetrafluoroborate; In N,N-dimethyl-formamide; Yield given; Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag;

Reference yield: 82.0%

diethyl 1-chloroethylphosphonate (10419-78-0) → 1-chloroethyl-phosphonochloridic acid, ethyl ester (742101-86-6) + ethyl phosphodichloridite (1498-51-7)

Guidance literature:

With trichlorophosphate; for 3h;

DOI:10.1080/00397919108019758

upstream raw materials:

(1,1-dichloro-ethyl)-phosphonic acid diethyl ester

4-methoxy-benzaldehyde

Downstream raw materials:

1-chloroethyl-phosphonochloridic acid, ethyl ester

ethyl phosphodichloridite

(E)-p-methoxyphenyl-2 methyl-1 epoxy-1,2 ethanephosphonate

(Z)-p-methoxyphenyl-2 methyl-1 epoxy-1,2 ethanephosphonate