Technology Process of C16H12N2O3
There total 3 articles about C16H12N2O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dihydrogen peroxide; sodium carbonate / acetone / 1 h / 5 - 20 °C
2: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 0.25 h / 20 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; dihydrogen peroxide; sodium carbonate; triethylamine;
In
acetone;
2: |Sonogashira Cross-Coupling / 2: |Sonogashira Cross-Coupling;
DOI:10.1007/s12039-012-0325-2
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium nitrite; hydrogenchloride / water / 0.5 h / 0 - 5 °C
1.2: 4 h / 5 - 20 °C
2.1: dihydrogen peroxide; sodium carbonate / acetone / 1 h / 5 - 20 °C
3.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 0.25 h / 20 °C / Inert atmosphere
With
hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; dihydrogen peroxide; sodium carbonate; triethylamine; sodium nitrite;
In
water; acetone;
1.1: |Sandmeyer Reaction / 1.2: |Sandmeyer Reaction / 3.1: |Sonogashira Cross-Coupling / 3.2: |Sonogashira Cross-Coupling;
DOI:10.1007/s12039-012-0325-2
- Guidance literature:
-
2-iodo-3-nitrobenzamide;
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine;
at 20 ℃;
for 0.25h;
Inert atmosphere;
4-n-methylphenylacetylene;
DOI:10.1007/s12039-012-0325-2
