[(S)-1-((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-2-phenyl-ethyl]-[1,3]dithiolan-2-ylidene-amine

Base Information

• Chemical Name: [(S)-1-((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-2-phenyl-ethyl]-[1,3]dithiolan-2-ylidene-amine
• CAS No.: 132075-98-0
• Molecular Formula: C₁₉H₂₈N₃OPS₂
• Molecular Weight: 409.557
• Mol file: 132075-98-0.mol

Synonyms:

Chemical Property of [(S)-1-((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-2-phenyl-ethyl]-[1,3]dithiolan-2-ylidene-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(S)-1-((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-2-phenyl-ethyl]-[1,3]dithiolan-2-ylidene-amine

There total 1 articles about [(S)-1-((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-2-phenyl-ethyl]-[1,3]dithiolan-2-ylidene-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl bromide (100-39-0) + ((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ5-benzo[1,3,2]diazaphosphol-2-ylmethyl)-[1,3]dithiolan-2-ylidene-amine (132075-94-6) → [(S)-1-((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ5-benzo[1,3,2]diazaphosphol-2-yl)-2-phenyl-ethyl]-[1,3]dithiolan-2-ylidene-amine (132075-98-0)

Guidance literature:

With potassium hexamethylsilazane; Yield given. Multistep reaction; 1) THF, toluene, -78 deg C, 10 min, 2) -78 deg C, 15 min;

DOI:10.1016/S0040-4039(00)97092-8

Reference yield: 86.0%

[(S)-1-((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ5-benzo[1,3,2]diazaphosphol-2-yl)-2-phenyl-ethyl]-[1,3]dithiolan-2-ylidene-amine (132075-98-0) → D-Phenylalanine phosphonate (66609-42-5)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide;

DOI:10.1016/S0040-4039(00)97092-8

upstream raw materials:

benzyl bromide

((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-ylmethyl)-[1,3]dithiolan-2-ylidene-amine

Downstream raw materials:

D-Phenylalanine phosphonate