Metanephrine

Base Information

• Chemical Name: Metanephrine
• CAS No.: 2282-54-4
• Molecular Formula: C₁₀H₁₅NO₃
• Molecular Weight: 197.234
• UNII: 1ZE0530JEJ
• DSSTox Substance ID: DTXSID80863478
• Nikkaji Number: J22.262C
• Wikipedia: Metanephrine
• Wikidata: Q412766
• NCI Thesaurus Code: C107556
• ChEMBL ID: CHEMBL775
• Mol file: 2282-54-4.mol

Synonyms:Metadrenaline;Metanephrine

Chemical Property of Metanephrine

Chemical Property:

• XLogP3: -1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 197.10519334
• Heavy Atom Count: 14
• Complexity: 165

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CNCC(C1=CC(=C(C=C1)O)OC)O

Technology Process of Metanephrine

There total 2 articles about Metanephrine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methoxy-4-hydroxyphenylglyoxal (32025-66-4) + methylamine (74-89-5) → metanephrine (2282-54-4,5001-33-2,105870-52-8)

Guidance literature:

With palladium on activated charcoal; ethanol; Hydrogenation;

Reference yield:

→ metanephrine (2282-54-4,5001-33-2,105870-52-8)

Guidance literature:

With methanol; palladium; Hydrogenation;

Reference yield:

metanephrine (2282-54-4,5001-33-2,105870-52-8) → normetanephrine + normetanephrine

Guidance literature:

With triethylamine; In methanol; water; at 20 ℃; enantioselective reaction; Resolution of racemate; Green chemistry;

DOI:10.3390/molecules24050833

upstream raw materials:

3-methoxy-4-hydroxyphenylglyoxal

methylamine

Downstream raw materials:

Metanephrin-pentafluorpropionat