Benzene, 1-methoxy-4-[(3-phenylpropoxy)methyl]-

Base Information

• Chemical Name: Benzene, 1-methoxy-4-[(3-phenylpropoxy)methyl]-
• CAS No.: 104330-36-1
• Molecular Formula: C17H20O2
• Molecular Weight: 256.345
• DSSTox Substance ID: DTXSID80447353
• Nikkaji Number: J484.673G
• Wikidata: Q82266215
• Mol file: 104330-36-1.mol

Synonyms:104330-36-1;Benzene, 1-methoxy-4-[(3-phenylpropoxy)methyl]-;SCHEMBL19210361;DTXSID80447353;4-Methoxybenzylhydrocinnamyl ether

Chemical Property of Benzene, 1-methoxy-4-[(3-phenylpropoxy)methyl]-

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 256.146329876
• Heavy Atom Count: 19
• Complexity: 215

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)COCCCC2=CC=CC=C2

Technology Process of Benzene, 1-methoxy-4-[(3-phenylpropoxy)methyl]-

There total 23 articles about Benzene, 1-methoxy-4-[(3-phenylpropoxy)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-Phenyl-1-propanol (122-97-4) + p-methoxybenzyl chloride (824-94-2) → p-methoxybenzyl 3-phenylpropyl ether (104330-36-1)

Guidance literature:

With sodium t-butanolate; In dimethyl sulfoxide; at 20 ℃; for 3h;

DOI:10.1016/j.tetlet.2019.151277

Reference yield: 95.0%

3-Phenyl-1-propanol (122-97-4) + 4-Methoxybenzyl alcohol (105-13-5) → p-methoxybenzyl 3-phenylpropyl ether (104330-36-1)

Guidance literature:

With ferric hydrogen sulphate; at 20 - 90 ℃; for 0.25h;

DOI:10.1007/s11164-015-2098-y

Reference yield: 94.0%

3-Phenyl-1-propanol (122-97-4) + 2,4,6-tris(4-methoxybenzyloxy)-1,3,5-triazine → p-methoxybenzyl 3-phenylpropyl ether (104330-36-1)

Guidance literature:

3-Phenyl-1-propanol; 2,4,6-tris(4-methoxybenzyloxy)-1,3,5-triazine; In ethyl acetate; at 20 ℃; for 0.166667h;

With trifluorormethanesulfonic acid; In ethyl acetate; for 0.266667h;

DOI:10.1055/s-0033-1339713

upstream raw materials:

3-Phenyl-1-propanol

p-methoxybenzyl chloride

2-(4-Methoxy-benzyl)-benzo[1,3,2]dithiazole 1,1,3,3-tetraoxide

4-methoxy-benzaldehyde

Downstream raw materials:

3-Phenyl-1-propanol

1-methyloxymethoxy-3-phenylpropane

4-bromo-phenol

3-phenyl-1-propyl 4-methoxybenzoate