Technology Process of 4,4'-bis(p-dimethylaminophenyl)-2,2'-bipyridine
There total 5 articles about 4,4'-bis(p-dimethylaminophenyl)-2,2'-bipyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4,4'-dibromo-2,2'-bipyridine; 4-(dimethylamino)benzene-boronic acid;
With
sodium carbonate;
In
water; toluene;
for 0.25h;
Inert atmosphere;
With
tetrakis(triphenylphosphine) palladium(0);
In
water; toluene;
for 14h;
Reflux;
DOI:10.1021/ic101909e
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sulfuric acid; nitric acid
2.1: Acetyl bromide / acetic acid / 4 h / 100 °C
3.1: phosphorus tribromide / acetonitrile / 4 h / Reflux
4.1: sodium carbonate / water; toluene / 0.25 h / Inert atmosphere
4.2: 14 h / Reflux
With
Acetyl bromide; sulfuric acid; nitric acid; phosphorus tribromide; sodium carbonate;
In
water; acetic acid; toluene; acetonitrile;
4.2: Suzuki coupling;
DOI:10.1021/ic101909e
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: phosphorus tribromide / acetonitrile / 4 h / Reflux
2.1: sodium carbonate / water; toluene / 0.25 h / Inert atmosphere
2.2: 14 h / Reflux
With
phosphorus tribromide; sodium carbonate;
In
water; toluene; acetonitrile;
2.2: Suzuki coupling;
DOI:10.1021/ic101909e
