4,4'-DIBROMO-2,2'-BIPYRIDINE-N,N'-DIOXIDE

Base Information

• Chemical Name: 4,4'-DIBROMO-2,2'-BIPYRIDINE-N,N'-DIOXIDE
• CAS No.: 84175-09-7
• Molecular Formula: C10H6Br2N2O2
• Molecular Weight: 345.978
• Hs Code.: 2933399090
• Mol file: 84175-09-7.mol

Synonyms:4,4'-Dibromo-2,2'-bipyridyl N,N'-dioxide;2,2'-Bipyridine,4,4'-dibromo-,1,1'-dioxide;4,4'-dibromo-2,2'-bipyridine N,N'-dioxide;

Chemical Property of 4,4'-DIBROMO-2,2'-BIPYRIDINE-N,N'-DIOXIDE

Chemical Property:

• Boiling Point: 621.756oC at 760 mmHg
• Flash Point: 329.826oC
• PSA: 50.92000
• Density: 1.945g/cm3
• LogP: 3.73560

Purity/Quality:

4,4'-DIBROMO-2,2'-BIPYRIDINE-1,1'-DIOXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4'-DIBROMO-2,2'-BIPYRIDINE-N,N'-DIOXIDE

There total 4 articles about 4,4'-DIBROMO-2,2'-BIPYRIDINE-N,N'-DIOXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4,4'-dinitro-2,2'-bipyridyl-N,N'-dioxide (51595-55-2) → 4,4'-dibromo-2,2'-bipyridine N,N'-dioxide (84175-09-7)

Guidance literature:

With Acetyl bromide; In acetic acid; at 100 ℃; for 4h;

DOI:10.1021/ic101909e

Reference yield:

[2,2]bipyridinyl (366-18-7) → 4,4'-dibromo-2,2'-bipyridine N,N'-dioxide (84175-09-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 35percent H₂O₂; AcOH / 80 °C

2: 90percent HNO₃; 30percent SO₃ / H₂SO₄ / 110 °C

3: AcBr / acetic acid / Heating

With Acetyl bromide; acetic acid; In sulfuric acid; acetic acid;

DOI:10.1021/ja0176705

Reference yield:

[2,2']bipyridinyl 1,1'-dioxide (7275-43-6) → 4,4'-dibromo-2,2'-bipyridine N,N'-dioxide (84175-09-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 90percent HNO₃; 30percent SO₃ / H₂SO₄ / 110 °C

2: AcBr / acetic acid / Heating

With Acetyl bromide; In sulfuric acid; acetic acid;

DOI:10.1021/ja0176705

upstream raw materials:

Acetyl bromide

4,4'-dinitro-2,2'-bipyridyl-N,N'-dioxide

[2,2]bipyridinyl

[2,2']bipyridinyl 1,1'-dioxide

Downstream raw materials:

C₂₂H₁₄N₄O₄

4,4'-diphenyl-2,2'-bipyridine

4,4'-bis(p-dimethylaminophenyl)-2,2'-bipyridine

4,4'-bis(p-methoxyphenyl)-2,2'-bipyridine

Refernces

• 1、 Han, Won-Sik,Han, Jung-Kyu,Kim, Hyun-Young,Choi, Mi Jin,Kang, Yong-Soo,Pac, Chyongjin,Kang, Sang Ook. "Electronic optimization of heteroleptic Ru(II) bipyridine complexes by remote substituents: Synthesis, characterization, and application to dye-sensitized solar cells". experimental part. p. 3271 - 3280. Retrieved 2011/06/22.
• 2、 Garcia-Lago, Ramon,Alonso-Gomez, Jose-Lorenzo,Sicre, Cristina,Cid, Maria-Magdalena. "Synthesis of 2,4-dibromopyridine and 4,4'-dibromo-2,2'-bipyridine. Efficient usage in selective bromine-substitution under palladium-catalysis". . p. 57 - 64. Retrieved 2008/09/20.