all-E-Heptaprenol

Base Information

• Chemical Name: all-E-Heptaprenol
• CAS No.: 32304-16-8
• Molecular Formula: C₃₅H₅₈O
• Molecular Weight: 494.845
• Mol file: 32304-16-8.mol

Synonyms:

Chemical Property of all-E-Heptaprenol

Chemical Property:

• Boiling Point: 583.7±19.0 °C(Predicted)
• PKA: 14.42±0.10(Predicted)
• Density: 0.887±0.06 g/cm3(Predicted)
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate

Purity/Quality:

99.3% ^*data from raw suppliers

all-E-Heptaprenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A polyprenyl alcohol with tumor cytotoxic activity.

Technology Process of all-E-Heptaprenol

There total 74 articles about all-E-Heptaprenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(2E,6E,10E,14E,18E,22E)-13-Methoxy-3,7,11,15,19,23,27-heptamethyl-octacosa-2,6,10,14,18,22,26-heptaen-1-ol (412348-10-8) → (all-E)-3,7,11,15,19,23,27-Heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-ol (32304-16-8)

Guidance literature:

(2E,6E,10E,14E,18E,22E)-13-Methoxy-3,7,11,15,19,23,27-heptamethyl-octacosa-2,6,10,14,18,22,26-heptaen-1-ol; With n-butyllithium; In tetrahydrofuran; at -78 ℃;

With lithium; ethylamine; In tetrahydrofuran; at -78 ℃; Further stages.;

DOI:10.1021/ja0127537

Reference yield: 83.0%

3,7,11,15,19,23,27-Heptamethyl-9-(phenylthio)octacosa-2,6,10,14,18,22,26-heptaenyl Benzyl Ether (74610-09-6) → (all-E)-3,7,11,15,19,23,27-Heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-ol (32304-16-8)

Guidance literature:

With lithium; ethylamine; In tetrahydrofuran; at -78 ℃; for 2h;

DOI:10.1021/jo01309a006

Reference yield: 82.0%

(all-E)-1-Benzyloxy-3,7,11,15,19,23,27-heptamethyl-13-phenylsulfanyloctacosa-2,6,10,14,18,22,26-heptaene → (all-E)-3,7,11,15,19,23,27-Heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-ol (32304-16-8)

Guidance literature:

With lithium; ethylamine; In tetrahydrofuran; at -78 ℃; for 2h;

DOI:10.1039/b008104n

upstream raw materials:

diethoxyphosphoryl-acetic acid ethyl ester

farnesylfarnesylacetone

2-((all-E)-4,8,12,16,20,24-hexamethyl-pentacosa-3,7,11,15,19,23-hexaenyl)-2-methyl-[1,3]dioxolane

3,7,11,15,19,23,27-Heptamethyl-9-(phenylthio)octacosa-2,6,10,14,18,22,26-heptaenyl Benzyl Ether

Downstream raw materials:

C₄₆H₅₇⁽²⁾H₇O₂

1-((2Z,6Z,10Z,14Z,18E,22E)-3,7,11,15,19,23,27-Heptamethyl-octacosa-2,6,10,14,18,22,26-heptaene-1-sulfonyl)-4-methyl-benzene