N-{[(Naphthalen-2-yl)oxy]acetyl}-L-phenylalanine

Base Information

Chemical Name:N-{[(Naphthalen-2-yl)oxy]acetyl}-L-phenylalanine
CAS No.:10441-31-3
Molecular Formula:C₂₁H₁₉NO₄
Molecular Weight:349.386
Hs Code.:
DSSTox Substance ID:DTXSID40542015
Nikkaji Number:J2.435.839I
Wikidata:Q82418521
Mol file:10441-31-3.mol

Synonyms:10441-31-3;N-{[(Naphthalen-2-yl)oxy]acetyl}-L-phenylalanine;(2S)-2-[2-(naphthalen-2-yloxy)acetamido]-3-phenylpropanoic acid;(S)-2-(2-(Naphthalen-2-yloxy)acetamido)-3-phenylpropanoic acid;SCHEMBL7356352;DTXSID40542015

Suppliers and Price of N-{[(Naphthalen-2-yl)oxy]acetyl}-L-phenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-{[(Naphthalen-2-yl)oxy]acetyl}-L-phenylalanine

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:349.13140809
Heavy Atom Count:26
Complexity:475

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)O)NC(=O)COC2=CC3=CC=CC=C3C=C2
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)COC2=CC3=CC=CC=C3C=C2

Technology Process of N-{[(Naphthalen-2-yl)oxy]acetyl}-L-phenylalanine

There total 2 articles about N-{[(Naphthalen-2-yl)oxy]acetyl}-L-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 120-23-0
(2-naphthoyl)oxyacetic acid

: 10441-31-3
2-[2-(Naphthalen-2-yloxy)-acetylamino]-3-phenyl-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 3 h / 90 °C

2: 2N NaOH / acetone; H₂O / 0 deg C, 20 min, pH: 9-11, then rt., 30 min

With sodium hydroxide; thionyl chloride; In water; acetone;
DOI:10.1248/cpb.36.4426