(2-Naphthyloxy)acetyl chloride

Base Information

Chemical Name:(2-Naphthyloxy)acetyl chloride
CAS No.:40926-77-0
Molecular Formula:C12H9ClO2
Molecular Weight:220.655
Hs Code.:2918990090
DSSTox Substance ID:DTXSID80482880
Nikkaji Number:J1.879.179J
Wikidata:Q82319722
Mol file:40926-77-0.mol

Synonyms:(2-NAPHTHYLOXY)ACETYL CHLORIDE;40926-77-0;2-(naphthalen-2-yloxy)acetyl chloride;2-naphthalen-2-yloxyacetyl chloride;Acetyl chloride, (2-naphthalenyloxy)-;2-naphthyloxyacetyl chloride;SCHEMBL1725156;DTXSID80482880;MFCD03421421;2-(naphthalen-2-yloxy)acetylchloride;AKOS005173160;EN300-236409;F2190-0097

Suppliers and Price of (2-Naphthyloxy)acetyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2-Naphthyloxy)acetylChloride
500mg
$ 335.00

TRC
(2-Naphthyloxy)acetylChloride
100mg
$ 80.00

Crysdot
2-(Naphthalen-2-yloxy)acetylchloride 97%
5g
$ 752.00

CHESS?
CC003085:(naphthalen-2-yloxy)acetylchloride 96
1 g
$ 288.00

CHESS?
CC003085:(naphthalen-2-yloxy)acetylchloride 96
5 g
$ 540.00

Chemenu
2-(Naphthalen-2-yloxy)acetylchloride 97%
5g
$ 711.00

American Custom Chemicals Corporation
(2-NAPHTHYLOXY)ACETYL CHLORIDE 95.00%
5MG
$ 502.24

Total 5 raw suppliers

Chemical Property of (2-Naphthyloxy)acetyl chloride

Chemical Property:

PSA：26.30000
LogP:2.98400
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:220.0291072
Heavy Atom Count:15
Complexity:230

Purity/Quality:

98%min ^*data from raw suppliers

(2-Naphthyloxy)acetylChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C=C(C=CC2=C1)OCC(=O)Cl
Uses (2-Naphthyloxy)acetyl Chloride serves as one of the reagents for the discovery of indoline-2-carboxamide derivatives as new classs of brain-penetrant inhibitors of trypanosoma brucei. Also in preparation and antibacterial activity of N-(phenylquinazolinonyl) aryl-amides by amidation of amino(phenyl)quinazolone with aroyl chlorides

Technology Process of (2-Naphthyloxy)acetyl chloride

There total 7 articles about (2-Naphthyloxy)acetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 120-23-0
(2-naphthoyl)oxyacetic acid

: 40926-77-0
(2-naphthyloxy)acetyl chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

: 135-19-3
β-naphthol

: 40926-77-0
(2-naphthyloxy)acetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: aq. KOH / 3 h / Heating

2: oxalyl chloride / toluene / 1 h / Heating

With potassium hydroxide; oxalyl dichloride; In toluene;
DOI:10.1021/jm960271d

Reference yield:

: 135-19-3
β-naphthol

: 40926-77-0
(2-naphthyloxy)acetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / H₂O / 2 h

2: SOCl₂ / benzene / Heating

With sodium hydroxide; thionyl chloride; In water; benzene; 1: Condensation / 2: Chlorination;
DOI:10.1016/S0223-5234(00)00128-8