Naphtho[2,3-c]furan-1,3-dione, 6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)-

Base Information

• Chemical Name: Naphtho[2,3-c]furan-1,3-dione, 6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)-
• CAS No.: 104423-00-9
• Molecular Formula: C41H32O8
• Molecular Weight: 652.68800
• Mol file: 104423-00-9.mol

Synonyms:6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)naphtho[2,3-c]furan-1,3-dione;4,5,8,9-Tetrakis-benzyloxy-6-methoxy-naphtho[2,3-c]furan-1,3-dione;

Chemical Property of Naphtho[2,3-c]furan-1,3-dione, 6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)-

Chemical Property:

• PSA: 89.52000
• LogP: 8.47500

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Naphtho[2,3-c]furan-1,3-dione, 6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)-

There total 8 articles about Naphtho[2,3-c]furan-1,3-dione, 6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl bromide (100-39-0) → 6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)naphtho<2,3-c>furan-1,3-dione (104423-00-9)

Guidance literature:

Multi-step reaction with 4 steps

1: K₂CO₃ / acetone

2: NaN(TMS)2 / tetrahydrofuran / 0 °C

3: K₂CO₃ / acetone

4: 1.) NaOH; 2.) Ac₂O / 1.) THF, aq.MeOH; 2.) heating

With sodium hydroxide; sodium hexamethyldisilazane; acetic anhydride; potassium carbonate; In tetrahydrofuran; acetone;

DOI:10.1021/ja00282a042

Reference yield:

dimethyl 6-methoxy-1,4,5,8-tetrakis(phenylmethoxy)-2,3-naphthalenedicarbocylate (104422-99-3) → 6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)naphtho<2,3-c>furan-1,3-dione (104423-00-9)

Guidance literature:

With sodium hydroxide; acetic anhydride; Yield given. Multistep reaction; 1.) THF, aq.MeOH; 2.) heating;

DOI:10.1021/ja00282a042

Reference yield:

dimethyl 3,6-dihydroxy-4-methoxyphthalate (103548-65-8) → 6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)naphtho<2,3-c>furan-1,3-dione (104423-00-9)

Guidance literature:

Multi-step reaction with 4 steps

1: K₂CO₃ / acetone

2: NaN(TMS)2 / tetrahydrofuran / 0 °C

3: K₂CO₃ / acetone

4: 1.) NaOH; 2.) Ac₂O / 1.) THF, aq.MeOH; 2.) heating

With sodium hydroxide; sodium hexamethyldisilazane; acetic anhydride; potassium carbonate; In tetrahydrofuran; acetone;

DOI:10.1021/ja00282a042

upstream raw materials:

1,4,5,8-Tetrakis-benzyloxy-6-methoxy-naphthalene-2,3-dicarboxylic acid

dimethyl 6-methoxy-1,4,5,8-tetrakis(phenylmethoxy)-2,3-naphthalenedicarbocylate

dimethyl 3,6-dioxocyclohexa-1,4-diene-1,2-dicarboxylate

benzyl bromide

Downstream raw materials:

3'-(diethoxymethyl)-3-hydroxy-1',6-dimethoxy-9'-(methoxymethoxy)-4,5,8,9-tetrakis(phenylmethoxy)spiro<2H-benzindene-2,8'-<8H>cyclopentisoquinolin>-1(3H)-one

3'-(diethoxymethyl)-1',6-dimethoxy-9'-(methoxymethoxy)-4,5,8,9-tetrakis(phenylmethoxy)spiro<2H-benzindene-2,8'-<8H>cyclopentisoquinoline>-1,3-dione

3-<3-(diethoxymethyl)-1-methoxy-9-(methoxymethoxy)-8H-cyclopentisoquinolin-8-ylidene>-7-methoxy-4,5,8,9-tetrakis(phenylmethoxy)naphtho<2,3-c>furan-1(3H)-one

3-<3-(diethoxymethyl)-1-methoxy-9-(methoxymethoxy)-8H-cyclopentisoquinolin-8-ylidene>-6-methoxy-4,5,8,9-tetrakis(phenylmethoxy)naphtho<2,3-c>furan-1(3H)-one