N-(4-aminophenyl)-2,2-dimethylpropanamide

Base Information

Chemical Name:N-(4-aminophenyl)-2,2-dimethylpropanamide
CAS No.:104478-93-5
Molecular Formula:C11H16N2O
Molecular Weight:192.261
Hs Code.:2924299090
DSSTox Substance ID:DTXSID70398880
Nikkaji Number:J238.278D
Wikidata:Q82201122
Mol file:104478-93-5.mol

Synonyms:N-(4-aminophenyl)-2,2-dimethylpropanamide;104478-93-5;N-(4-Aminophenyl)pivalamide;4-Pivaloylaminoaniline;SCHEMBL1913557;DTXSID70398880;CQBPZUVCJMMOLJ-UHFFFAOYSA-N;BBL034739;MFCD00186306;STL417934;AKOS000104213;VS-12655;CS-0244400;EN300-27708;E85848;Z57442174

Suppliers and Price of N-(4-aminophenyl)-2,2-dimethylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(4-Aminophenyl)-2,2-dimethylpropanamide
500mg
$ 110.00

TRC
N-(4-Aminophenyl)-2,2-dimethylpropanamide
100mg
$ 60.00

Matrix Scientific
N-(4-Aminophenyl)-2,2-dimethylpropanamide
500mg
$ 199.00

Crysdot
N-(4-Aminophenyl)pivalamide 95+%
5g
$ 704.00

ChemBridge Corporation
N-(4-aminophenyl)-2,2-dimethylpropanamide 95%
5 g
$ 205.00

American Custom Chemicals Corporation
N-(4-AMINOPHENYL)-2,2-DIMETHYLPROPANAMIDE 95.00%
5G
$ 1005.43

American Custom Chemicals Corporation
N-(4-AMINOPHENYL)-2,2-DIMETHYLPROPANAMIDE 95.00%
2.5G
$ 852.21

American Custom Chemicals Corporation
N-(4-AMINOPHENYL)-2,2-DIMETHYLPROPANAMIDE 95.00%
1G
$ 648.81

Total 7 raw suppliers

Chemical Property of N-(4-aminophenyl)-2,2-dimethylpropanamide

Chemical Property:

Vapor Pressure:0.00114mmHg at 25°C
Boiling Point:300.2oC at 760 mmHg
Flash Point:135.4oC
PSA：55.12000
Density:1.102g/cm3
LogP:2.90760
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:192.126263138
Heavy Atom Count:14
Complexity:200

Purity/Quality:

98%Min ^*data from raw suppliers

N-(4-Aminophenyl)-2,2-dimethylpropanamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)NC1=CC=C(C=C1)N

Technology Process of N-(4-aminophenyl)-2,2-dimethylpropanamide

There total 9 articles about N-(4-aminophenyl)-2,2-dimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 56619-95-5
2,2-dimethyl-N-(4-nitrophenyl)propionamide

: 104478-93-5
2,2-dimethyl-N-(4-aminophenyl)propionamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; at 40 ℃; for 24h; under 2625.21 Torr;
DOI:10.1002/chem.200400716

Reference yield: 87.0%

: N-acetyl-N'-pivaloyl-p-phenylenediamine

: 104478-93-5
2,2-dimethyl-N-(4-aminophenyl)propionamide

Guidance literature:: N-acetyl-N'-pivaloyl-p-phenylenediamine; With boron trifluoride - methanol (1/1); In methanol; for 3h; Reflux;

With ammonia; In methanol; water; Cooling;
DOI:10.1016/j.tetlet.2015.12.087

Reference yield:

: 3282-30-2
pivaloyl chloride

: 104478-93-5
2,2-dimethyl-N-(4-aminophenyl)propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / N-methyl-2-pyrrolidone; Et₃N; LiCl / 2 h / 80 °C

2: 94 percent / H₂ / Pd/C / tetrahydrofuran; methanol / 24 h / 40 °C / 2625.21 Torr

With 1-methyl-pyrrolidin-2-one; hydrogen; triethylamine; lithium chloride; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1002/chem.200400716