(+/-)-(6S*,6aR*,12aR*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ⁴-benzocycloocta<1,2>thiazine-6-oxide

Base Information

• Chemical Name: (+/-)-(6S*,6aR*,12aR*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ⁴-benzocycloocta<1,2>thiazine-6-oxide
• CAS No.: 134970-91-5
• Molecular Formula: C₂₁H₂₅NOS
• Molecular Weight: 339.502

Synonyms:

Chemical Property of (+/-)-(6S*,6aR*,12aR*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ⁴-benzocycloocta<1,2>thiazine-6-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-(6S*,6aR*,12aR*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ⁴-benzocycloocta<1,2>thiazine-6-oxide

There total 4 articles about (+/-)-(6S*,6aR*,12aR*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ⁴-benzocycloocta<1,2>thiazine-6-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cis-Cyclooctene (931-88-4,931-87-3,25267-51-0) + N-phenyl-S-(4-methylphenyl)sulfoximidoyl chloride (123552-85-2) → (+/-)-(6S*,6aS*,12aS*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ4-benzocycloocta<1,2>thiazine-6-oxide (134970-91-5,135093-42-4,138922-17-5,138922-18-6) + (+/-)-(6S*,6aR*,12aR*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ4-benzocycloocta<1,2>thiazine-6-oxide (134970-91-5,135093-42-4,138922-17-5,138922-18-6)

Guidance literature:

With aluminium trichloride; In dichloromethane; at -78 ℃; Yield given. Yields of byproduct given;

DOI:10.1021/jo00017a015

Reference yield:

cis-Cyclooctene (931-88-4,931-87-3,25267-51-0) + N-phenyl-S-(4-methylphenyl)sulfoximidoyl chloride (123552-85-2) → (+/-)-(6S*,6aS*,12aS*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ4-benzocycloocta<1,2>thiazine-6-oxide (134970-91-5,135093-42-4,138922-17-5,138922-18-6) + (+/-)-(6S*,6aR*,12aR*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ4-benzocycloocta<1,2>thiazine-6-oxide (134970-91-5,135093-42-4,138922-17-5,138922-18-6)

Guidance literature:

With aluminium trichloride; In dichloromethane; at -78 ℃; Yield given. Yields of byproduct given;

DOI:10.1021/jo00017a015

Reference yield:

1-(p-tolylsulfinyl)aniline (6873-54-7) → (+/-)-(6S*,6aS*,12aS*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ4-benzocycloocta<1,2>thiazine-6-oxide (134970-91-5,135093-42-4,138922-17-5,138922-18-6)

Guidance literature:

Multi-step reaction with 2 steps

1: tert-butyl hypochlorite / CH₂Cl₂ / 0.17 h / -78 °C

2: AlCl₃ / CH₂Cl₂ / -78 °C

With aluminium trichloride; tert-butylhypochlorite; In dichloromethane;

DOI:10.1021/jo00017a015

upstream raw materials:

cis-Cyclooctene

N-phenyl-S-(4-methylphenyl)sulfoximidoyl chloride

1-(p-tolylsulfinyl)aniline

Downstream raw materials:

4-methyl-N-(2-(cyclooct-1-enyl)-phenyl)benzenesulfinamide

2-(cyclooct-1-enyl)aniline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 134970-91-5 (+/-)-(6S*,6aR*,12aR*)-6a,7,8,9,10,11,12,12a-octahydro-6-(4-methylphenyl)-6λ⁴-benzocycloocta<1,2>thiazine-6-oxide

Send

Send

Metric Ton KG G Pound L ML

Send

Send