C₂₅H₃₁N₅O₃S

Base Information

• Chemical Name: C₂₅H₃₁N₅O₃S
• CAS No.: 1374858-34-0
• Molecular Formula: C₂₅H₃₁N₅O₃S
• Molecular Weight: 481.619
• Mol file: 1374858-34-0.mol

Synonyms:

Chemical Property of C₂₅H₃₁N₅O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₁N₅O₃S

There total 11 articles about C₂₅H₃₁N₅O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H29N5O2S (1374858-25-9) + acetyl chloride (75-36-5) → C25H31N5O3S (1374858-34-0)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2012.03.025

Reference yield:

4-fluoro-2-methoxybenzaldehyde (450-83-9) → C25H31N5O3S (1374858-34-0)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium carbonate / dimethyl sulfoxide / 80 - 120 °C

2: iodine / N,N-dimethyl acetamide / 1 h / 130 °C

3: hydrogenchloride / ethyl acetate / 4 h / 20 °C

4: triethylamine / dichloromethane / 1 h / 20 °C

With hydrogenchloride; iodine; potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl acetamide; dimethyl sulfoxide; ethyl acetate;

DOI:10.1016/j.bmcl.2012.03.025

Reference yield:

[cyclohexyl(hydroxy)methylidene]propanedinitrile (553672-03-0) → C25H31N5O3S (1374858-34-0)

Guidance literature:

Multi-step reaction with 8 steps

1: trichlorophosphate / Reflux

2: ammonium hydroxide / 0.5 h / 20 °C

3: hydrogen sulfide; triethylamine / benzene

4: dihydrogen peroxide / methanol / 50 °C

5: sulfuric acid / 0.5 h / 80 °C

6: iodine / N,N-dimethyl acetamide / 1 h / 130 °C

7: hydrogenchloride / ethyl acetate / 4 h / 20 °C

8: triethylamine / dichloromethane / 1 h / 20 °C

With hydrogenchloride; ammonium hydroxide; sulfuric acid; hydrogen sulfide; dihydrogen peroxide; iodine; triethylamine; trichlorophosphate; In methanol; dichloromethane; N,N-dimethyl acetamide; ethyl acetate; benzene;

DOI:10.1016/j.bmcl.2012.03.025

upstream raw materials:

[cyclohexyl(hydroxy)methylidene]propanedinitrile

tert-butyl 4-(4-formyl-3-methoxyphenyl)-1,4-diazepane-1-carboxylate

C₂₈H₃₇N₅O₄S

3-amino-2-cyano-3-cyclohexylprop-2-enethioamide