S-acetyl-PEG4-Propargyl

Base Information

Chemical Name:S-acetyl-PEG4-Propargyl
CAS No.:1422540-88-2
Molecular Formula:C₁₃H₂₂O₅S
Molecular Weight:290.381
Hs Code.:

Synonyms:

Suppliers and Price of S-acetyl-PEG4-Propargyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
Acetylthio-PEG4-Alkyne
50MG
$ 270.00

TCI Chemical
Acetylthio-PEG4-Alkyne
250MG
$ 939.00

Chem-Impex
Acetylthio-PEG4-alkyne,≥98%(GC) ≥98%(GC)
50MG
$ 298.19

Chem-Impex
Acetylthio-PEG4-alkyne,98%(GC) 98%(GC)
250MG
$ 1128.96

BroadPharm
S-acetyl-PEG4-propargyl 98%
500 MG
$ 660.00

BroadPharm
S-acetyl-PEG4-propargyl 98%
250 MG
$ 460.00

BroadPharm
S-acetyl-PEG4-propargyl 98%
100 MG
$ 260.00

BroadPharm
S-acetyl-PEG4-propargyl 98%
1 G
$ 990.00

AK Scientific
S-Acetyl-PEG4-Propargyl
250mg
$ 1267.00

Total 10 raw suppliers

Chemical Property of S-acetyl-PEG4-Propargyl

Chemical Property:

Solubility.:Soluble in DMSO, DCM, DMF

Purity/Quality:

97% ^*data from raw suppliers

Acetylthio-PEG4-Alkyne ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description S-acetyl-PEG4-propargyl is a PEG linker containing a sulfur acetyl group and a propargyl moiety. The sulfur acetyl group can be deprotected to produce a thiol compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of the compounds in the aqueous media.

Technology Process of S-acetyl-PEG4-Propargyl

There total 3 articles about S-acetyl-PEG4-Propargyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1233816-83-5
methanesulfonic acid 2-{2-[2-(2-prop-2-ynyloxyethoxy)ethoxy]ethoxy}ethyl ester

: 10387-40-3
potassium thioacetate

: 1422540-88-2
C₁₃H₂₂O₅S

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 15h;
DOI:10.1039/c2ob26968f

Reference yield:

: 112-60-7
Tetraethylene glycol

: 1422540-88-2
C₁₃H₂₂O₅S

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran / 20 °C

1.2: 16 h / 20 - 60 °C

2.1: triethylamine / dichloromethane / 4 h / 0 - 20 °C

3.1: N,N-dimethyl-formamide / 15 h / 20 °C

With sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c2ob26968f

Reference yield:

: 87450-10-0
3,6,9,12-tetraoxapentadec-14-yn-1-ol

: 1422540-88-2
C₁₃H₂₂O₅S

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 4 h / 0 - 20 °C

2: N,N-dimethyl-formamide / 15 h / 20 °C

With triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c2ob26968f