2-Naphthalenecarboxylic acid, 3-hydroxy-4-[[2-hydroxy-5-(1-methylethyl)-3-oxo-1,4,6-cycloheptatrien-1- yl](4-methoxyphenyl)methyl]-

Base Information

• Chemical Name: 2-Naphthalenecarboxylic acid, 3-hydroxy-4-[[2-hydroxy-5-(1-methylethyl)-3-oxo-1,4,6-cycloheptatrien-1- yl](4-methoxyphenyl)methyl]-
• CAS No.: 104598-49-4
• Molecular Formula: C29H26O6
• Molecular Weight: 470.522
• Mol file: 104598-49-4.mol

Synonyms:

Chemical Property of 2-Naphthalenecarboxylic acid, 3-hydroxy-4-[[2-hydroxy-5-(1-methylethyl)-3-oxo-1,4,6-cycloheptatrien-1- yl](4-methoxyphenyl)methyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Naphthalenecarboxylic acid, 3-hydroxy-4-[[2-hydroxy-5-(1-methylethyl)-3-oxo-1,4,6-cycloheptatrien-1- yl](4-methoxyphenyl)methyl]-

There total 3 articles about 2-Naphthalenecarboxylic acid, 3-hydroxy-4-[[2-hydroxy-5-(1-methylethyl)-3-oxo-1,4,6-cycloheptatrien-1- yl](4-methoxyphenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-(α-ethoxy-4-methoxybenzyl)-6-isopropyltropolone (92832-11-6) + 3-Hydroxy-2-naphthoic acid (92-70-6) → 2-hydroxy-1-<α-(2-hydroxy-6-isopropyltropon-3-yl)-4-methoxybenzyl>-3-naphthoic acid (104598-49-4)

Guidance literature:

at 120 ℃; for 0.5h;

DOI:10.1021/jm00384a020

Reference yield:

4-methoxybenzaldehyde diethylacetal (2403-58-9) → 2-hydroxy-1-<α-(2-hydroxy-6-isopropyltropon-3-yl)-4-methoxybenzyl>-3-naphthoic acid (104598-49-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / toluene / 20 h / Heating

2: 89 percent / 0.5 h / 120 °C

In toluene;

DOI:10.1021/jm00384a020

Reference yield:

hinokitiol (499-44-5) → 2-hydroxy-1-<α-(2-hydroxy-6-isopropyltropon-3-yl)-4-methoxybenzyl>-3-naphthoic acid (104598-49-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / toluene / 20 h / Heating

2: 89 percent / 0.5 h / 120 °C

In toluene;

DOI:10.1021/jm00384a020

upstream raw materials:

3-(α-ethoxy-4-methoxybenzyl)-6-isopropyltropolone

3-Hydroxy-2-naphthoic acid

4-methoxybenzaldehyde diethylacetal

hinokitiol