1-(Diethoxymethyl)-4-methoxybenzene

Base Information

• Chemical Name: 1-(Diethoxymethyl)-4-methoxybenzene
• CAS No.: 2403-58-9
• Deprecated CAS: 28135-52-6
• Molecular Formula: C12H18 O3
• Molecular Weight: 210.273
• Hs Code.: 2909309090
• European Community (EC) Number: 219-288-6
• NSC Number: 20033
• UNII: XNU9E8U6PY
• DSSTox Substance ID: DTXSID7051896
• Nikkaji Number: J76.327F
• Wikidata: Q63392925
• Mol file: 2403-58-9.mol

Synonyms:1-(Diethoxymethyl)-4-methoxybenzene;2403-58-9;p-(Diethoxymethyl)anisole;Benzene, 1-(diethoxymethyl)-4-methoxy-;4-Methoxybenzaldehyde diethyl acetal;Anisaldenyde diethyl acetal;XNU9E8U6PY;EINECS 219-288-6;NSC 20033;NSC-20033;para-Methoxybenzaldehyde diethyl acetal;AI3-06443;UNII-XNU9E8U6PY;4-(Diethoxymethyl)anisole;p - (diethoxymethyl)anisole;SCHEMBL1472635;DTXSID7051896;1-Diethoxymethyl-4-methoxybenzene;p-methoxybenzaldehyde diethylacetal;NSC20033;MFCD00672800;PARA-ANISALDEHYDE DIETHYL ACETAL;Q63392925

Chemical Property of 1-(Diethoxymethyl)-4-methoxybenzene

Chemical Property:

• Refractive Index: 1.4920
• Boiling Point: 103-104°C/3.5mm
• Flash Point: 103-104°C/3.5mm
• PSA: 27.69000
• Density: 1.06
• LogP: 2.76680
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 210.125594432
• Heavy Atom Count: 15
• Complexity: 147

Purity/Quality:

99% ^*data from raw suppliers

4-METHOXYBENZALDEHYDE DIETHYL ACETAL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(C1=CC=C(C=C1)OC)OCC

Technology Process of 1-(Diethoxymethyl)-4-methoxybenzene

There total 14 articles about 1-(Diethoxymethyl)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

ethanol (64-17-5) + 4-methoxy-benzaldehyde (123-11-5) → 4-methoxybenzaldehyde diethylacetal (2403-58-9)

Guidance literature:

With orthoformic acid triethyl ester; at 20 ℃; for 1.5h;

DOI:10.1080/00397910802219361

Reference yield: 95.0%

4-methoxy-benzaldehyde (123-11-5) + orthoformic acid triethyl ester (122-51-0) → 4-methoxybenzaldehyde diethylacetal (2403-58-9)

Guidance literature:

With tropylium tetrafluoroborate; In acetonitrile; at 70 ℃; for 5h; Inert atmosphere; Green chemistry;

DOI:10.1039/c7gc01519d

Reference yield: 92.0%

4-methoxy-aniline (104-94-9) + orthoformic acid triethyl ester (122-51-0) → 4-methoxybenzaldehyde diethylacetal (2403-58-9)

Guidance literature:

aminosulfonic acid; at 25 ℃; for 3h;

DOI:10.1081/SCC-200039314

upstream raw materials:

ethanol

4-methoxy-benzaldehyde

ethyl formimidate hydrochloride

orthoformic acid triethyl ester

Downstream raw materials:

N,N'-(4-methoxy-benzylidene)-bis-carbamic acid diethyl ester

4-methoxybenzaldehyde di-n-butyl acetal

Aethoxy-<4-methoxy-phenyl>-methylbromid

5-[ethoxy(4-methoxyphenyl)methyl]quinolin-6-ol