N-(4-Chloro-phenyl)-N-{2-[(4-chloro-phenyl)-trifluoromethanesulfonyl-amino]-2-oxo-acetyl}-C,C,C-trifluoro-methanesulfonamide

Base Information

• Chemical Name: N-(4-Chloro-phenyl)-N-{2-[(4-chloro-phenyl)-trifluoromethanesulfonyl-amino]-2-oxo-acetyl}-C,C,C-trifluoro-methanesulfonamide
• CAS No.: 71537-30-9
• Molecular Formula: C₁₆H₈Cl₂F₆N₂O₆S₂
• Molecular Weight: 573.278
• Mol file: 71537-30-9.mol

Synonyms:

Chemical Property of N-(4-Chloro-phenyl)-N-{2-[(4-chloro-phenyl)-trifluoromethanesulfonyl-amino]-2-oxo-acetyl}-C,C,C-trifluoro-methanesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-Chloro-phenyl)-N-{2-[(4-chloro-phenyl)-trifluoromethanesulfonyl-amino]-2-oxo-acetyl}-C,C,C-trifluoro-methanesulfonamide

There total 2 articles about N-(4-Chloro-phenyl)-N-{2-[(4-chloro-phenyl)-trifluoromethanesulfonyl-amino]-2-oxo-acetyl}-C,C,C-trifluoro-methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-aniline (106-47-8) → N-(4-Chloro-phenyl)-N-{2-[(4-chloro-phenyl)-trifluoromethanesulfonyl-amino]-2-oxo-acetyl}-C,C,C-trifluoro-methanesulfonamide (71537-30-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂

2: Et₃N / 1,2-dimethoxy-ethane

With triethylamine; In 1,2-dimethoxyethane; dichloromethane;

DOI:10.1021/jo01337a020

Reference yield:

oxalyl dichloride (79-37-8) + N-[4-chlorophenyl]-1,1,1-trifluoromethanesulfonamide (23384-04-5) → N-(4-Chloro-phenyl)-N-{2-[(4-chloro-phenyl)-trifluoromethanesulfonyl-amino]-2-oxo-acetyl}-C,C,C-trifluoro-methanesulfonamide (71537-30-9)

Guidance literature:

With triethylamine; In 1,2-dimethoxyethane;

DOI:10.1021/jo01337a020

upstream raw materials:

oxalyl dichloride

N-[4-chlorophenyl]-1,1,1-trifluoromethanesulfonamide

4-chloro-aniline