N-(1H-benzimidazol-2-yl)-5-chloro-2-methoxybenzamide

Base Information

Chemical Name:N-(1H-benzimidazol-2-yl)-5-chloro-2-methoxybenzamide
CAS No.:81268-49-7
Molecular Formula:C₁₅H₁₂ClN₃O₂
Molecular Weight:301.732
Hs Code.:
DSSTox Substance ID:DTXSID801323823
ChEMBL ID:CHEMBL1595582
Mol file:81268-49-7.mol

Synonyms:N-(1H-benzimidazol-2-yl)-5-chloro-2-methoxybenzamide;Oprea1_504430;Oprea1_709977;MLS001174579;CHEMBL1595582;DTXSID801323823;KUC106857N;KSC-09-227D;STK315460;AKOS001058573;81268-49-7;SMR000591546;AB00723358-01;SR-01000050895;SR-01000050895-1;Z27664760;N~1~-(1H-1,3-BENZIMIDAZOL-2-YL)-5-CHLORO-2-METHOXYBENZAMIDE

Suppliers and Price of N-(1H-benzimidazol-2-yl)-5-chloro-2-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-(1H-BENZIMIDAZOL-2-YL)-5-CHLORO-2-METHOXYBENZAMIDE 95.00%
5MG
$ 500.41

Total 0 raw suppliers

Chemical Property of N-(1H-benzimidazol-2-yl)-5-chloro-2-methoxybenzamide

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:301.0618043
Heavy Atom Count:21
Complexity:382

Purity/Quality:: N-(1H-BENZIMIDAZOL-2-YL)-5-CHLORO-2-METHOXYBENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)Cl)C(=O)NC2=NC3=CC=CC=C3N2

Technology Process of N-(1H-benzimidazol-2-yl)-5-chloro-2-methoxybenzamide

There total 2 articles about N-(1H-benzimidazol-2-yl)-5-chloro-2-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.5%

: 934-32-7
1H-benzimidazol-2-amine

: 29568-33-0
2-methoxy-5-chlorobenzoyl chloride

: 81268-49-7
N-(1H-Benzoimidazol-2-yl)-5-chloro-2-methoxy-benzamide

Guidance literature:: With pyridine; for 5h; Ambient temperature;

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 81268-49-7
N-(1H-Benzoimidazol-2-yl)-5-chloro-2-methoxy-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1) Br₂ / 1) water, 5 deg C; 2) water, room temperature, 5 h.

2: 46.5 percent / pyridine / 5 h / Ambient temperature

With pyridine; bromine;