C₂₂H₂₇FN₆O₂S

Base Information

Chemical Name:C₂₂H₂₇FN₆O₂S
CAS No.:1416137-39-7
Molecular Formula:C₂₂H₂₇FN₆O₂S
Molecular Weight:458.56
Hs Code.:

C<sub>22</sub>H<sub>27</sub>FN<sub>6</sub>O<sub>2</sub>S

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₂H₂₇FN₆O₂S

Chemical Property:

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Technology Process of C₂₂H₂₇FN₆O₂S

There total 4 articles about C₂₂H₂₇FN₆O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₆H₂₁FN₄O₂S

: 111196-81-7
2-chloro-5-ethylpyrimidine

: 1416137-39-7
C₂₂H₂₇FN₆O₂S

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 120 ℃;
DOI:10.1016/j.bmcl.2012.10.119

Reference yield:

: 1416137-47-7
C₂₁H₂₉FN₄O₄S

: 1416137-39-7
C₂₂H₂₇FN₆O₂S

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / methanol / 20 °C

2: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 120 °C

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; In methanol; dimethyl sulfoxide;
DOI:10.1016/j.bmcl.2012.10.119

Reference yield:

: 76180-33-1
[2-fluoro-4-(methylthio)phenyl]amine

: 1416137-39-7
C₂₂H₂₇FN₆O₂S

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tris(acetoxy)borohydride; acetic acid / 1,2-dichloro-ethane / 20 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C

3: hydrogenchloride / methanol / 20 °C

4: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 120 °C

With hydrogenchloride; sodium tris(acetoxy)borohydride; acetic acid; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane; dimethyl sulfoxide; 1,2-dichloro-ethane;
DOI:10.1016/j.bmcl.2012.10.119