(1R,2R)-2-(Chloromethyl)cyclohexane-1-carbonitrile

Base Information

Chemical Name:(1R,2R)-2-(Chloromethyl)cyclohexane-1-carbonitrile
CAS No.:10479-49-9
Molecular Formula:C8H12ClN
Molecular Weight:157.643
Hs Code.:
DSSTox Substance ID:DTXSID20511022
Wikidata:Q82369620
Mol file:10479-49-9.mol

Synonyms:(1R,2R)-2-(Chloromethyl)cyclohexane-1-carbonitrile;10479-49-9;SCHEMBL11101930;DTXSID20511022;PWTGUPWAFPCHHN-YUMQZZPRSA-N;AKOS006384511;trans-2-(chloromethyl)cyclohexanenitrile

Suppliers and Price of (1R,2R)-2-(Chloromethyl)cyclohexane-1-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (1R,2R)-2-(Chloromethyl)cyclohexane-1-carbonitrile

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:157.0658271
Heavy Atom Count:10
Complexity:147

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(C(C1)CCl)C#N
Isomeric SMILES:C1CC[C@H]([C@@H](C1)CCl)C#N

Technology Process of (1R,2R)-2-(Chloromethyl)cyclohexane-1-carbonitrile

There total 1 articles about (1R,2R)-2-(Chloromethyl)cyclohexane-1-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 10479-40-0,90006-44-3
(+/-)-trans-2-Chlormethyl-cyclohex-4-en-1-carbonitril

: 10479-49-9
trans-2-(chloromethyl)cyclohexanecarbonitrile

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr;

Reference yield:

: 10479-49-9
trans-2-(chloromethyl)cyclohexanecarbonitrile

: 2-[4-(1-Carboxy-ethyl)-phenoxymethyl]-cyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Na / 1.) ethanol, 2.) reflux, 48 h

2: KOH / bis-(2-hydroxy-ethyl) ether / 5 h / 250 °C

With potassium hydroxide; sodium; In diethylene glycol;
DOI:10.1021/jm00164a006

Reference yield:

: 10479-49-9
trans-2-(chloromethyl)cyclohexanecarbonitrile

: 2-(4-Carboxymethyl-phenoxymethyl)-cyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Na / 1.) ethanol, 2.) reflux, 48 h

2: KOH / bis-(2-hydroxy-ethyl) ether / 5 h / 250 °C

With potassium hydroxide; sodium; In diethylene glycol;
DOI:10.1021/jm00164a006