p-methylbenzaldehyde oxime

Base Information

• Chemical Name: p-methylbenzaldehyde oxime
• CAS No.: 140461-27-4
• Molecular Formula: C₈H₉NO
• Molecular Weight: 135.166
• Mol file: 140461-27-4.mol

Synonyms:

Chemical Property of p-methylbenzaldehyde oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-methylbenzaldehyde oxime

There total 20 articles about p-methylbenzaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-methyl-benzaldehyde (104-87-0) → p-methylbenzaldehyde oxime (3235-02-7,3717-15-5,3717-16-6,140461-26-3,140461-27-4)

Guidance literature:

With hydroxylamine hydrochloride; sodium carbonate; In ethanol; at 20 ℃;

DOI:10.1039/c2ob26699g

Reference yield: 93.0%

4-Methylbenzyl alcohol (589-18-4) → p-methylbenzaldehyde oxime (3235-02-7,3717-15-5,3717-16-6,140461-26-3,140461-27-4)

Guidance literature:

4-Methylbenzyl alcohol; With dihydrogen peroxide; at 20 ℃; for 0.166667h; Green chemistry;

With hydroxylamine hydrochloride; for 4h; Catalytic behavior; Green chemistry;

DOI:10.1016/j.molstruc.2019.03.008

Reference yield: 90.0%

para-bromotoluene (106-38-7) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → p-methylbenzaldehyde oxime (3235-02-7,3717-15-5,3717-16-6,140461-26-3,140461-27-4)

Guidance literature:

para-bromotoluene; With n-butyllithium; In tetrahydrofuran; hexane; at -50 ℃; for 0.5h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -50 - 20 ℃; for 1h; Inert atmosphere;

With hydroxylamine hydrochloride; potassium carbonate; In tetrahydrofuran; hexane; at 20 ℃; for 2h; Reagent/catalyst; Temperature; Inert atmosphere;

DOI:10.1016/j.tet.2018.06.044

upstream raw materials:

piperidine

4-Methyl-benzaldehyde O-(2,4-dinitro-phenyl)-oxime

2-(4-methylphenyl)-1,3-dioxolane

N-methyl-4-tolylnitrone

Downstream raw materials:

N-hydroxy-4-methylbenzenecarboximidoyl chloride

4-Methyl-O-<2,4-dimethyl-phenoxycarbimidoyl>benzaldoxim

(5R,7S,8R,9R,10S)-8,9,10-Tris(benzyloxy)-7-methoxy-3-(4-methylphenyl)-1,6-dioxa-2-azaspiro[4.5]dec-2-ene

4-Formyl-1,1-diphenyl-3-p-tolyl-2,4a,5,6-tetrahydro-1H-[2]pyrindine-5,6-dicarboxylic acid dimethyl ester