Benzoic acid, 4-nitro-,2-(1-methylethylidene)hydrazide

Base Information

• Chemical Name: Benzoic acid, 4-nitro-,2-(1-methylethylidene)hydrazide
• CAS No.: 7462-05-7
• Molecular Formula: C10H11 N3 O3
• Molecular Weight: 221.216
• Mol file: 7462-05-7.mol

Synonyms:Benzoicacid, 4-nitro-, (1-methylethylidene)hydrazide (9CI); NSC 404142; p-Nitrobenzoicacid isopropylidene hydrazide

Chemical Property of Benzoic acid, 4-nitro-,2-(1-methylethylidene)hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-nitro-,2-(1-methylethylidene)hydrazide

There total 4 articles about Benzoic acid, 4-nitro-,2-(1-methylethylidene)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N-amino-(4-nitrophenyl)carboxamide (636-97-5) + acetone (67-64-1) → N-(1-methylethylidene)-4-nitrobenzohydrazide (7462-05-7)

Guidance literature:

In hexane; Heating / reflux;

Reference yield:

N-amino-(4-nitrophenyl)carboxamide (636-97-5) + acetone (67-64-1) → anbhz (7462-05-7)

Guidance literature:

In ethanol; Reflux;

DOI:10.1016/j.poly.2012.02.007

Reference yield:

4-nitrobenzoic acid methyl ester (619-50-1) → N-(1-methylethylidene)-4-nitrobenzohydrazide (7462-05-7)

Guidance literature:

Multi-step reaction with 2 steps

1: alcohol; hydrazine hydrate

2: water

With ethanol; water; hydrazine hydrate;

upstream raw materials:

N-amino-(4-nitrophenyl)carboxamide

acetone

4-nitrobenzoic acid methyl ester

ethyl 4-nitrobenzoate

Downstream raw materials:

Co((CH₃)2CNNC(O)C₆H₄NO₂-p)2(C₅H₅N)2

nickel(II) acetone 4-nitrobenzoylhydrazone

Co((CH₃)2CNNHC(O)C₆H₄NO₂-p)2Cl₂

3-[2-(4-chlorophenyl)-2-oxoethyl]-3-hydroxy-2-(4-nitrobenzoyl)-6-phenyl-2,3-dihydropyridazin-4(1H)-one