Technology Process of C22H15ClN6O
There total 8 articles about C22H15ClN6O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
dimethyl sulfoxide;
at 130 ℃;
DOI:10.1021/ja2058583
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen; triethylamine / N,N-dimethyl-formamide / 2 h
2: potassium carbonate / dimethyl sulfoxide / 130 °C
With
palladium 10% on activated carbon; hydrogen; potassium carbonate; triethylamine;
In
dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/ja2058583
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrogenchloride; sodium nitrite / water / 1 h / 0 °C
1.2: 1 h / 60 - 80 °C
2.1: boron tribromide / dichloromethane / 13 h / -78 - 20 °C / Inert atmosphere
3.1: bis(triphenylphosphine)palladium(II) dichloride; triethylamine / N,N-dimethyl-formamide / 3 h / 20 - 140 °C / Inert atmosphere
4.1: potassium carbonate / dimethyl sulfoxide / 130 °C
With
hydrogenchloride; bis(triphenylphosphine)palladium(II) dichloride; boron tribromide; potassium carbonate; triethylamine; sodium nitrite;
In
dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
3.1: Heck reaction;
DOI:10.1021/ja2058583
