Ethyl 2-(tert-butoxy)acetate

Base Information

• Chemical Name: Ethyl 2-(tert-butoxy)acetate
• CAS No.: 42415-65-6
• Molecular Formula: C₈H₁₆O₃
• Molecular Weight: 160.213
• European Community (EC) Number: 867-687-4
• Nikkaji Number: J994.149E
• Mol file: 42415-65-6.mol

Synonyms:ethyl 2-(tert-butoxy)acetate;42415-65-6;Ethyl 2-[(2-methylpropan-2-yl)oxy]acetate;ethyl2-(tert-butoxy)acetate;SCHEMBL5607319;tert-Butoxyacetic acid ethyl ester;AKOS009256197;CS-0225642;EN300-124528

Chemical Property of Ethyl 2-(tert-butoxy)acetate

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 160.109944368
• Heavy Atom Count: 11
• Complexity: 124

Purity/Quality:

ethyl2-(tert-butoxy)acetate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=O)COC(C)(C)C

Technology Process of Ethyl 2-(tert-butoxy)acetate

There total 2 articles about Ethyl 2-(tert-butoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

diazoacetic acid ethyl ester (623-73-4) + tert-butyl alcohol (75-65-0) → tert-butoxy-acetic acid ethyl ester (42415-65-6)

Guidance literature:

rhodium(II) acetate; at 22 ℃;

DOI:10.1016/0040-4020(82)80031-8

Reference yield:

→ tert-butoxy-acetic acid ethyl ester (42415-65-6)

Guidance literature:

tert.-Butyloxy-essigsaeure;

Reference yield:

tert-butoxy-acetic acid ethyl ester (42415-65-6) → tert-butoxyacetic acid (13211-32-0)

Guidance literature:

With water; sodium hydroxide; In methanol; for 9.58333h;

upstream raw materials:

diazoacetic acid ethyl ester

tert-butyl alcohol

Downstream raw materials:

tert-butoxyacetic acid