C₆₅H₆₉N₂O₁₅P

Base Information

• Chemical Name: C₆₅H₆₉N₂O₁₅P
• CAS No.: 193953-65-0
• Molecular Formula: C₆₅H₆₉N₂O₁₅P
• Molecular Weight: 1149.24
• Mol file: 193953-65-0.mol

Synonyms:

Chemical Property of C₆₅H₆₉N₂O₁₅P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₅H₆₉N₂O₁₅P

There total 9 articles about C₆₅H₆₉N₂O₁₅P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4,6-Tetra-O-benzyl-D-glucopyranose (4291-69-4,6386-24-9,6564-72-3,59531-24-7,69257-52-9,78184-89-1,78609-16-2,78609-17-3,78609-18-4,96553-53-6,104111-61-7,131347-08-5,4132-28-9) → C65H69N2O15P (193953-65-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) n-BuLi; 2.) HMPA / tetrahydrofuran / 2 h / -10 °C

2: trimethylsilyl trifluoromethanesulfonate, EtCN / 1 h / -78 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; trimethylsilyl trifluoromethanesulfonate; propiononitrile; In tetrahydrofuran;

DOI:10.1016/S0040-4039(97)01122-2

Reference yield:

C38H47N2O7P (143520-19-8) → C65H69N2O15P (193953-65-0)

Guidance literature:

Multi-step reaction with 5 steps

1: H₂ / Pd(OH)2/C / methanol / 48 h

2: imidazole / acetonitrile / 1 h / -5 °C

3: DMAP / pyridine / 2 h

4: TBAF, AcOH / tetrahydrofuran / 1 h

5: trimethylsilyl trifluoromethanesulfonate, EtCN / 1 h / -78 °C

With 1H-imidazole; dmap; trimethylsilyl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; hydrogen; acetic acid; propiononitrile; palladium dihydroxide; In tetrahydrofuran; pyridine; methanol; acetonitrile;

DOI:10.1016/S0040-4039(97)01122-2

Reference yield:

2,3,4,5-tetra-O-acetyl-D-glucopyranose (3947-62-4,6207-76-7,19235-21-3,22554-70-7,22860-22-6,47339-09-3,57884-82-9,62057-79-8,70191-05-8,109525-54-4,140147-37-1,10343-06-3) → C65H69N2O15P (193953-65-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) n-BuLi; 2.) HMPA / tetrahydrofuran / 2 h / -10 °C

2: Et₃N / methanol / 48 h

3: imidazole / acetonitrile / 1 h / -5 °C

4: DMAP / pyridine / 2 h

5: TBAF, AcOH / tetrahydrofuran / 1 h

6: trimethylsilyl trifluoromethanesulfonate, EtCN / 1 h / -78 °C

With 1H-imidazole; N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; n-butyllithium; trimethylsilyl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; acetic acid; triethylamine; propiononitrile; In tetrahydrofuran; pyridine; methanol; acetonitrile;

DOI:10.1016/S0040-4039(97)01122-2

upstream raw materials:

C₃₈H₄₇N₂O₇P

2,3,4-tri-O-benzoyl-α-D-glucopyranosyl tetramethylphosphoroamidate

2,3,4,6-Tetra-O-benzyl-D-glucopyranose

2,3,4,5-tetra-O-acetyl-D-glucopyranose

Downstream raw materials:

C₆₅H₇₅N₂O₁₂P