Technology Process of C12H17NO2
There total 4 articles about C12H17NO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: water; sodium hydroxide / methanol / 1 h / 20 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / acetonitrile / 1 h / 20 °C / Inert atmosphere
With
water; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; sodium hydroxide;
In
methanol; acetonitrile;
DOI:10.1248/cpb.59.1523
- Guidance literature:
-
Multi-step reaction with 3 steps
1: palladium on activated charcoal; hydrogen / methanol / 1 h
2: water; sodium hydroxide / methanol / 1 h / 20 °C
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / acetonitrile / 1 h / 20 °C / Inert atmosphere
With
palladium on activated charcoal; water; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; sodium hydroxide;
In
methanol; acetonitrile;
DOI:10.1248/cpb.59.1523
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C / Inert atmosphere
2: tetrakis(triphenylphosphine) palladium(0) / toluene / 2 h / 110 °C / Inert atmosphere
3: palladium on activated charcoal; hydrogen / methanol / 1 h
4: water; sodium hydroxide / methanol / 1 h / 20 °C
5: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / acetonitrile / 1 h / 20 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); palladium on activated charcoal; water; hydrogen; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; sodium hydroxide;
In
methanol; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1248/cpb.59.1523