2,4-Dichloro-5-(trifluoromethyl)quinazoline

Base Information

• Chemical Name: 2,4-Dichloro-5-(trifluoromethyl)quinazoline
• CAS No.: 134517-56-9
• Molecular Formula: C₉H₃Cl₂F₃N₂
• Molecular Weight: 267.037
• DSSTox Substance ID: DTXSID70601149
• Wikidata: Q82497624

Synonyms:2,4-Dichloro-5-(trifluoromethyl)quinazoline;134517-56-9;MFCD09954879;SCHEMBL3668991;DTXSID70601149;MGMZEWORTYBDQY-UHFFFAOYSA-N;AKOS022173677;GS-0633;SB13561;SY346586;CS-0186500;D82699

Chemical Property of 2,4-Dichloro-5-(trifluoromethyl)quinazoline

Chemical Property:

• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 265.9625380
• Heavy Atom Count: 16
• Complexity: 262

Purity/Quality:

99%, ^*data from raw suppliers

2,4-Dichloro-5-(trifluoromethyl)quinazoline >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=C2C(=C1)N=C(N=C2Cl)Cl)C(F)(F)F

Technology Process of 2,4-Dichloro-5-(trifluoromethyl)quinazoline

There total 3 articles about 2,4-Dichloro-5-(trifluoromethyl)quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-trifluoromethylquinazoline-2,4(1H,3H)-dione (959236-92-1) → 2,4-dichloro-5-trifluoromethylquinazoline (134517-56-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; trichlorophosphate; Reflux;

DOI:10.1021/jm901379s

Reference yield: 80.0%

→ 2,4-dichloro-5-trifluoromethylquinazoline (134517-56-9)

Guidance literature:

Reference yield:

6-trifluoromethyl anthranilic acid (314-46-5) + urea (57-13-6) → 2,4-dichloro-5-trifluoromethylquinazoline (134517-56-9)

Guidance literature:

6-trifluoromethyl anthranilic acid; urea; at 210 ℃; for 0.25h;

With N,N-dimethyl-aniline; trichlorophosphate; at 135 ℃; for 5h;

upstream raw materials:

6-trifluoromethyl anthranilic acid

urea

5-trifluoromethylquinazoline-2,4(1H,3H)-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 134517-56-9 2,4-dichloro-5-trifluoromethylquinazoline

Send

Send

Metric Ton KG G Pound L ML

Send

Send