2-(2,4-dichlorophenoxy)-N'-[(E)-phenylmethylidene]acetohydrazide

Base Information

• Chemical Name: 2-(2,4-dichlorophenoxy)-N'-[(E)-phenylmethylidene]acetohydrazide
• CAS No.: 2496-37-9
• Molecular Formula: C₁₅H₁₂Cl₂N₂O₂
• Molecular Weight: 323.178
• European Community (EC) Number: 657-176-2
• ChEMBL ID: CHEMBL2086625
• Mol file: 2496-37-9.mol

Synonyms:2-(2,4-dichlorophenoxy)-N'-[(E)-phenylmethylidene]acetohydrazide;CHEMBL2086625;STK023256;AKOS000568013;BRD-K70270885-001-01-7;N'-benzylidene-2-(2,4-dichlorophenoxy)acetohydrazide

Chemical Property of 2-(2,4-dichlorophenoxy)-N'-[(E)-phenylmethylidene]acetohydrazide

Chemical Property:

• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 322.0275830
• Heavy Atom Count: 21
• Complexity: 360

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=NNC(=O)COC2=C(C=C(C=C2)Cl)Cl
• Isomeric SMILES: C1=CC=C(C=C1)/C=N/NC(=O)COC2=C(C=C(C=C2)Cl)Cl

Technology Process of 2-(2,4-dichlorophenoxy)-N'-[(E)-phenylmethylidene]acetohydrazide

There total 4 articles about 2-(2,4-dichlorophenoxy)-N'-[(E)-phenylmethylidene]acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzaldehyde (100-52-7) + 2,4-dichlorophenoxyacetylhydrazine (28236-62-6) → 1-[(2,4-dichlorophenoxy)acetyl]-2-benzylidenehydrazine (2496-37-9)

Guidance literature:

at 83 ℃; for 0.0333333h; microwave irradiation;

Reference yield:

ethyl 2,4-dichlorophenoxyacetate (533-23-3) → 1-[(2,4-dichlorophenoxy)acetyl]-2-benzylidenehydrazine (2496-37-9)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol; hydrazine hydrate

2: ethanol

With ethanol; hydrazine hydrate monohydrate;

Reference yield:

2-(2,4-dichlorophenoxy)acetyl chloride (774-74-3) → 1-[(2,4-dichlorophenoxy)acetyl]-2-benzylidenehydrazine (2496-37-9)

Guidance literature:

Multi-step reaction with 3 steps

2: ethanol; hydrazine hydrate

3: ethanol

With ethanol; hydrazine hydrate monohydrate;

upstream raw materials:

benzaldehyde

2,4-dichlorophenoxyacetylhydrazine

2,4-Dichlorophenoxyacetic acid

ethyl 2,4-dichlorophenoxyacetate