4-methoxy-salicylaldehyde acetylhydrazone

Base Information

• Chemical Name: 4-methoxy-salicylaldehyde acetylhydrazone
• CAS No.: 154387-94-7
• Molecular Formula: C₁₀H₁₂N₂O₃
• Molecular Weight: 208.217
• Mol file: 154387-94-7.mol

Synonyms:

Chemical Property of 4-methoxy-salicylaldehyde acetylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methoxy-salicylaldehyde acetylhydrazone

There total 1 articles about 4-methoxy-salicylaldehyde acetylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxy-5-methoxybenzaldehyde (672-13-9) + acetic acid hydrazide (1068-57-1) → 4-methoxy-salicylaldehyde acetylhydrazone (154387-94-7)

Guidance literature:

In ethanol; for 12h; Inert atmosphere; Reflux;

DOI:10.1021/acs.orglett.0c00669

Reference yield:

4-methoxy-salicylaldehyde acetylhydrazone (154387-94-7) → 2-acetyl-4-methoxy-benzaldehyde (1193731-69-9)

Guidance literature:

With lead(IV) tetraacetate; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c00669

Reference yield:

tris(triphenylphosphine)ruthenium(II) chloride (15529-49-4,41756-81-4) + 4-methoxy-salicylaldehyde acetylhydrazone (154387-94-7) → [Ru(N-(acetyl)-N'-(5-OCH3-salicylidene)hydrazine(-2H))(PPh3)2Cl]

Guidance literature:

With air; In methanol; equimolar Ru-compound added to alcoholic soln. of organic ligand; stirred in air at room temp. for 8 h; collected by filtration; washed with n-hexane; dried in air; dissolved in CH2Cl2; transferred to neutral Al2O3 column; eluted with CH2Cl2; recrystallized from CH2Cl2/n-hexane 1:1 mixt.; elem. anal.;

DOI:10.1016/j.poly.2007.10.027

upstream raw materials:

2-hydroxy-5-methoxybenzaldehyde

acetic acid hydrazide

Downstream raw materials:

2-acetyl-4-methoxy-benzaldehyde