(pentafluoro phenyl) glyoxylic acid ethyl ester

Base Information

• Chemical Name: (pentafluoro phenyl) glyoxylic acid ethyl ester
• CAS No.: 38442-37-4
• Molecular Formula: C₁₀H₅F₅O₃
• Molecular Weight: 268.14
• Mol file: 38442-37-4.mol

Synonyms:

Chemical Property of (pentafluoro phenyl) glyoxylic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (pentafluoro phenyl) glyoxylic acid ethyl ester

There total 3 articles about (pentafluoro phenyl) glyoxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

pentafluorophenylmagnesium chloride (879-06-1) + oxalic acid diethyl ester (95-92-1) → (pentafluoro phenyl) glyoxylic acid ethyl ester (38442-37-4)

Guidance literature:

at -30 - -20 ℃;

Reference yield: 38.0%

pentafluorophenyl lithium (1076-44-4) + oxalic acid diethyl ester (95-92-1) → (pentafluoro phenyl) glyoxylic acid ethyl ester (38442-37-4) + Decafluorobenzil (19555-07-8)

Guidance literature:

reaction at -78°C, 3 hours, addition of C6H5Li and stirring for 36 hours;;

DOI:10.1039/P19720002464

Reference yield:

→ (pentafluoro phenyl) glyoxylic acid ethyl ester (38442-37-4)

Guidance literature:

Pentafluorphenyllithium, Oxalsaeurediethylester, Phenyllithium;

upstream raw materials:

pentafluorophenylmagnesium chloride

oxalic acid diethyl ester

pentafluorophenyl lithium

Downstream raw materials:

2,3,4,5,6-pentafluorobenzoylformic acid

Refernces