1,3-benzodioxol-5-yl-phenylmethanol

Base Information

• Chemical Name: 1,3-benzodioxol-5-yl-phenylmethanol
• CAS No.: 123436-14-6
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.247
• Mol file: 123436-14-6.mol

Synonyms:

Chemical Property of 1,3-benzodioxol-5-yl-phenylmethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-benzodioxol-5-yl-phenylmethanol

There total 15 articles about 1,3-benzodioxol-5-yl-phenylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

piperonal (120-57-0,30024-74-9) + phenylboronic acid (98-80-6) → 1,3-benzodioxol-5-yl(phenyl)methanol (4382-91-6,123436-14-6)

Guidance literature:

With hexakis{[3-(2,4,6-trimethylphenyl)imidazolio]methyl}benzene hexabromide; potassium tert-butylate; chloro(1,5-cyclooctadiene)rhodium(I) dimer; In 1,4-dioxane; water; at 80 ℃; for 16h;

DOI:10.1016/j.jorganchem.2005.09.022

Reference yield: 85.0%

piperonal (120-57-0,30024-74-9) + potassium phenyltrifluoborate → 1,3-benzodioxol-5-yl(phenyl)methanol (4382-91-6,123436-14-6)

Guidance literature:

With caesium carbonate; bis(η3-allyl-μ-chloropalladium(II)); In water; toluene; at 100 ℃; for 2h;

DOI:10.1021/jo801352h

Reference yield: 84.0%

piperonal (120-57-0,30024-74-9) + trimethyl(phenyl)stannane (934-56-5) → 1,3-benzodioxol-5-yl(phenyl)methanol (4382-91-6,123436-14-6)

Guidance literature:

With bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; In tetrahydrofuran; at 60 ℃; for 5h;

DOI:10.1016/S0040-4020(03)00586-6

upstream raw materials:

piperonal

5-(Bromo-phenyl-methyl)-benzo[1,3]dioxole

phenylmagnesium bromide

bromobenzene

Downstream raw materials:

3-benzo[1,3]dioxol-5-yl-3-phenyl-propionic acid

(3,4-methylenedioxyphenyl) phenyl methanone

5--benzylbenzo[d][1,3]dioxole

6-Benzyl-benzo[1,3]dioxol-5-ylamine