Technology Process of methyl (1R,2S,4S)-2-(<(tert-butyl)diphenylsilyloxy>methyl)-4-(formyloxy)cyclopentaneacetate
There total 7 articles about methyl (1R,2S,4S)-2-(<(tert-butyl)diphenylsilyloxy>methyl)-4-(formyloxy)cyclopentaneacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran;
at 0 ℃;
for 0.5h;
Yield given;
DOI:10.1002/hlca.19930760207
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 89 percent / imidazole / CH2Cl2 / 1 h / Ambient temperature
2: 1) (+)-(1R)-α-pinene, BH3-THF, 2) 30percent aq. H2O2, 3N aq. NaOH
3: pyridinium chlorochromate, Celite / CH2Cl2 / 4 h / Ambient temperature
4: 3-chloroperbenzoic acid, NaHCO3 / CH2Cl2 / 18 h / 4 °C
5: methanol / Heating
6: PPh3, diethyl azodicarboxylate / tetrahydrofuran / 0.5 h / 0 °C
With
1H-imidazole; sodium hydroxide; borane-THF; Celite; dihydrogen peroxide; sodium hydrogencarbonate; 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; pyridinium chlorochromate; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1002/hlca.19930760207
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1) (+)-(1R)-α-pinene, BH3-THF, 2) 30percent aq. H2O2, 3N aq. NaOH
2: pyridinium chlorochromate, Celite / CH2Cl2 / 4 h / Ambient temperature
3: 3-chloroperbenzoic acid, NaHCO3 / CH2Cl2 / 18 h / 4 °C
4: methanol / Heating
5: PPh3, diethyl azodicarboxylate / tetrahydrofuran / 0.5 h / 0 °C
With
sodium hydroxide; borane-THF; Celite; dihydrogen peroxide; sodium hydrogencarbonate; 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; pyridinium chlorochromate; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1002/hlca.19930760207
