17β-estradiol enanthate

Base Information

• Chemical Name: 17β-estradiol enanthate
• CAS No.: 10093-54-6
• Molecular Formula: C₂₅H₃₆O₃
• Molecular Weight: 384.559
• Mol file: 10093-54-6.mol

Synonyms:

Chemical Property of 17β-estradiol enanthate

Chemical Property:

• Boiling Point: 509.5±50.0 °C(Predicted)
• Density: 1.11±0.1 g/cm3(Predicted)

Purity/Quality:

HPLC ≥ 98% ^*data from raw suppliers

17α-Estra-1,3,5(10)-triene-3,17-diol-17-heptanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 17α-Estra-1,3,5(10)-triene-3,17-diol-17-heptanoate can be used as part of a method for neuroprotection and for treating and retarding the effects of neurodegenerative diseases such as Alzheimer’s disease.

Technology Process of 17β-estradiol enanthate

There total 6 articles about 17β-estradiol enanthate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

estradiol (50-28-2) + Heptanoic acid chloride (2528-61-2) → 17β-estradiol enanthate (10093-54-6,4956-37-0)

Guidance literature:

estradiol; Heptanoic acid chloride; With pyridine; In toluene; at 20 - 35 ℃; for 1h;

With potassium carbonate; In methanol; water; at 35 - 40 ℃; for 1h; Solvent;

Reference yield:

estradiol (50-28-2) + Heptanoic acid chloride (2528-61-2) → 17β-estradiol enanthate (10093-54-6,4956-37-0) + 3,17-diheptanoic acid-17β-estradiol (7732-97-0)

Guidance literature:

With pyridine; In toluene; at 20 - 35 ℃; for 1h; Solvent;

Reference yield:

3,17-diheptanoic acid-17β-estradiol (7732-97-0) → 17β-estradiol enanthate (10093-54-6,4956-37-0)

Guidance literature:

With benzoic acid benzyl ester; at 160 ℃;

DOI:10.1002/jps.2600680621

upstream raw materials:

3-benzoyloxy-17β-heptanoyloxy-estra-1,3,5(10)-triene

19-nortestosterone

Heptanoic acid chloride

3,17-diheptanoic acid-17β-estradiol

Downstream raw materials:

estradiol-17β 3-β-D-glucopyranoside

estradiol

Refernces

• 1、 -. "Synthetic technology for oestradiol 17-heptanoate". Paragraph 0015-0020. . Retrieved 2019/04/04.