C₃₀H₄₈N₂O₃SSi

Base Information

• Chemical Name: C₃₀H₄₈N₂O₃SSi
• CAS No.: 911381-71-0
• Molecular Formula: C₃₀H₄₈N₂O₃SSi
• Molecular Weight: 544.874
• Mol file: 911381-71-0.mol

Synonyms:

Chemical Property of C₃₀H₄₈N₂O₃SSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₄₈N₂O₃SSi

There total 1 articles about C₃₀H₄₈N₂O₃SSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H35NO2SSi + N-benzyl-3-pyrrolidinone (775-16-6) → C30H48N2O3SSi (911381-71-0)

Guidance literature:

C₁₉H₃₅NO₂SSi; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

N-benzyl-3-pyrrolidinone; In tetrahydrofuran; hexane; at -78 ℃; for 0.833333h; Further stages.;

DOI:10.1055/s-2006-942427

Reference yield:

C30H48N2O3SSi (911381-71-0) + chloro-trimethyl-silane (75-77-4) → C33H56N2O3SSi2

Guidance literature:

With dmap; N,N-dimethyl-ethanamine; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1055/s-2006-942427

Reference yield:

C30H48N2O3SSi (911381-71-0) → (+)-[SS,N(1S),2S,3R,3aR,6aR]-N-{1-[tert-butyl(dimethyl)silanyloxymethyl]-2-methyl-propyl}-2,5-dibenzyly-6a-(p-tolyl-sulfonimidoylmethyl)octahydro-pyrrolo[3,4-b]pyrrol-3-ol

Guidance literature:

Multi-step reaction with 4 steps

1.1: EtMe₂N; 4-dimethylaminopyridine / CH₂Cl₂ / 16 h / 20 °C

2.1: n-BuLi / toluene; hexane / 0.83 h / -78 °C

2.2: 2.079 g / KO-t-Bu; n-BuLi / toluene; hexane / 3.75 h / -78 - 20 °C

3.1: n-BuLi / toluene; hexane / 0.25 h / -78 °C

3.2: ClTi(O-i-Pr)3 / toluene; hexane / 1.25 h / -78 - 20 °C

3.3: toluene; hexane; tetrahydrofuran / 2 h / 0 °C

4.1: 196 mg / piperidine / toluene; hexane / 14 h / 20 °C

With piperidine; dmap; n-butyllithium; N,N-dimethyl-ethanamine; In hexane; dichloromethane; toluene;

DOI:10.1055/s-2006-942427

upstream raw materials:

N-benzyl-3-pyrrolidinone

Downstream raw materials:

(-)-[S_S,N(1S)]-N-{1-[tert-butyl(dimethyl)silanyloxymethyl]-2-methyl-propyl}-1-benzyl-3-(p-tolyl-sulfonimidomethyl)-2,5-dihydro-1H-pyrrole