ethyl 4-amino-3-nitrobenzimidate

Base Information

• Chemical Name: ethyl 4-amino-3-nitrobenzimidate
• CAS No.: 165596-29-2
• Molecular Formula: C₉H₁₁N₃O₃
• Molecular Weight: 209.205
• Mol file: 165596-29-2.mol

Synonyms:

Chemical Property of ethyl 4-amino-3-nitrobenzimidate

Chemical Property:

Purity/Quality:

ethyl4-amino-3-nitrobenzimidate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 4-amino-3-nitrobenzimidate

There total 1 articles about ethyl 4-amino-3-nitrobenzimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

ethanol (64-17-5) + 4-Amino 3-nitro-benzonitrile (6393-40-4) → ethyl 4-amino-3-nitrobenzenecarboximidate (165596-29-2)

Guidance literature:

With hydrogenchloride; Cooling with ice;

Reference yield: 73.0%

ethyl 4-amino-3-nitrobenzenecarboximidate (165596-29-2) + 4-(4-methylpiperazino)-1,2-diaminobenzene (54998-08-2) → 4-[5'-(4'-methylpiperazin-1'-yl)benzimidazol-2'-yl]-2-nitroaniline (23623-05-4)

Guidance literature:

With acetic acid; In ethanol; at 100 ℃; for 4h;

Reference yield:

ethyl 4-amino-3-nitrobenzenecarboximidate (165596-29-2) → 4-<5'-(4''-methylpiperazin-1''-yl)benzimidazol-2'-yl>benzene-1,2-diamine (23491-49-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / ethanol / 4 h / 100 °C

2: palladium 10% on activated carbon; hydrogen / ethanol

With palladium 10% on activated carbon; hydrogen; acetic acid; In ethanol;

upstream raw materials:

ethanol

4-Amino 3-nitro-benzonitrile

Downstream raw materials:

4-[5'-(4'-methylpiperazin-1'-yl)benzimidazol-2'-yl]-2-nitroaniline

4-<5'-(4''-methylpiperazin-1''-yl)benzimidazol-2'-yl>benzene-1,2-diamine

Refernces