2-Methoxy-1-pyridin-2-ylethanone

Base Information

• Chemical Name: 2-Methoxy-1-pyridin-2-ylethanone
• CAS No.: 105729-06-4
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.165
• Hs Code.: 2933399090
• European Community (EC) Number: 860-916-9
• DSSTox Substance ID: DTXSID60547047
• Wikidata: Q82425050
• Mol file: 105729-06-4.mol

Synonyms:2-methoxy-1-pyridin-2-ylethanone;105729-06-4;2-Methoxy-1-(pyridin-2-yl)ethanone;2-Methoxy-1-(pyridin-2-yl)ethan-1-one;DTXSID60547047;2-Methoxy-1-(2-pyridinyl)ethanone;MFCD09864437;AKOS006281443;SB53851;2-Methoxy-1-pyridin-2-ylethanone, AldrichCPR;G46353;EN300-4274858

Chemical Property of 2-Methoxy-1-pyridin-2-ylethanone

Chemical Property:

• Vapor Pressure: 0.0337mmHg at 25°C
• Boiling Point: 242.6oC at 760 mmHg
• Flash Point: 100.5oC
• PSA: 39.19000
• Density: 1.102g/cm3
• LogP: 0.91070
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 151.063328530
• Heavy Atom Count: 11
• Complexity: 136

Purity/Quality:

98% ^*data from raw suppliers

2-Methoxy-1-pyridin-2-ylethanone ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC(=O)C1=CC=CC=N1

Technology Process of 2-Methoxy-1-pyridin-2-ylethanone

There total 1 articles about 2-Methoxy-1-pyridin-2-ylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

methanol (67-56-1) + trimethyl-(1-pyridinylvinyloxy)-silane (87221-66-7) → 2-<(methoxymethyl)carbonyl>pyridine (105729-06-4)

Guidance literature:

With iodosylbenzene; boron trifluoride diethyl etherate; In dichloromethane; at -70 ℃; for 3.5h;

DOI:10.1021/jo00377a027

Reference yield: 60.0%

2-<(methoxymethyl)carbonyl>pyridine (105729-06-4) + 4-Phenyl-3-thiosemicarbazide (5351-69-9) → 2-(α-methoxyacetyl)pyridine N4-phenylthiosemicarbazone

Guidance literature:

With acetic acid; In methanol; for 2h; Heating;

upstream raw materials:

methanol

trimethyl-(1-pyridinylvinyloxy)-silane