Technology Process of ethyl 2,3,5-tri-O-benzoyl-1-thio-α-D-arabinofuranoside
There total 1 articles about ethyl 2,3,5-tri-O-benzoyl-1-thio-α-D-arabinofuranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetyl chloride / 20 °C
1.2: 20 °C / Cooling with ice
2.1: boron trifluoride diethyl etherate / dichloromethane / 5.33 h / 0 °C
With
boron trifluoride diethyl etherate; acetyl chloride;
In
dichloromethane;
DOI:10.1039/c3cc00042g
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 2.09 g / NaOMe / methanol / 20 °C
2: 65 percent / pyridine / 3 h / 20 °C
3: 59 percent / BEMP / acetonitrile
4: nBu4NF / tetrahydrofuran / 0.25 h / 20 °C
5: pyridine / 4 h
With
pyridine; tetrabutyl ammonium fluoride; sodium methylate; 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine;
In
tetrahydrofuran; methanol; acetonitrile;
1: deprotection / 2: Etherification / 3: Etherification / 4: deprotection / 5: Acetylation;
DOI:10.1016/S0008-6215(99)00078-6
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 2.09 g / NaOMe / methanol / 20 °C
2: 65 percent / pyridine / 3 h / 20 °C
3: 59 percent / BEMP / acetonitrile
With
pyridine; sodium methylate; 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine;
In
methanol; acetonitrile;
1: deprotection / 2: Etherification / 3: Etherification;
DOI:10.1016/S0008-6215(99)00078-6
