DesMethyl FluoroMetholone

Base Information

Chemical Name:DesMethyl FluoroMetholone
CAS No.:426-20-0
Molecular Formula:C₂₁H₂₇FO₄
Molecular Weight:362.441
Hs Code.:
Mol file:426-20-0.mol

Synonyms:

Suppliers and Price of DesMethyl FluoroMetholone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DesmethylFluorometholone
50mg
$ 1190.00

Total 6 raw suppliers

Chemical Property of DesMethyl FluoroMetholone

Chemical Property:

Melting Point:>173°C (dec.)
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

DesmethylFluorometholone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Desmethyl Fluorometholone acts as a glucocorticoid, a steroid for treatment of ocular inflammation. It is an impurity of Fluorometholone (F593145) synthesis.

Technology Process of DesMethyl FluoroMetholone

There total 11 articles about DesMethyl FluoroMetholone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 382-66-1
9-fluoro-11β,17-dihydroxy-21-methanesulfonyloxy-pregna-1,4-diene-3,20-dione

: 426-20-0
9-fluoro-11β,17-dihydroxy-pregna-1,4-diene-3,20-dione

Guidance literature:: With acetic acid; sodium iodide;
DOI:10.1021/ja01620a076

Reference yield:

: 514-36-3
fludrocortisone acetate

: 426-20-0
9-fluoro-11β,17-dihydroxy-pregna-1,4-diene-3,20-dione

Guidance literature:: Multi-step reaction with 5 steps

1: palladium / Hydrogenation

2: bromine; acetic acid / Erhitzen des Reaktionsprodukts mit 2,4,6-Trimethyl-pyridin

3: aqueous methanol.K₂CO₃

5: NaI; acetic acid

With bromine; potassium carbonate; palladium; acetic acid; sodium iodide;
DOI:10.1021/ja01620a076

Reference yield:

: 52-21-1
prednisolone 21-acetate

: 426-20-0
9-fluoro-11β,17-dihydroxy-pregna-1,4-diene-3,20-dione

Guidance literature:: Multi-step reaction with 7 steps

1: methanesulfonyl chloride; pyridine

2: aqueous HClO₄

3: potassium acetate; ethanol

4: HF

5: aqueous methanol.K₂CO₃

7: NaI; acetic acid

With pyridine; perchloric acid; ethanol; hydrogen fluoride; potassium acetate; potassium carbonate; acetic acid; methanesulfonyl chloride; sodium iodide;
DOI:10.1021/ja01620a076