Technology Process of (S)-3-((5E,9E)-(R)-2-Isopropenyl-5,9-dimethyl-11-phenylsulfanyl-undeca-5,9-dienyl)-2,2-dimethyl-oxirane
There total 23 articles about (S)-3-((5E,9E)-(R)-2-Isopropenyl-5,9-dimethyl-11-phenylsulfanyl-undeca-5,9-dienyl)-2,2-dimethyl-oxirane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 15 steps
1: 2,4-dinitrophenol / toluene / 140 °C
2: Zn(BH4)2
3: Py, DMAP
4: p-TsOH / tetrahydrofuran; H2O
5: NaIO4 / tetrahydrofuran; H2O
6: NaBH4 / methanol
7: 2M aq. NaOH
8: PPTS
9: DEAD, Ph3P, LiI / dimethylformamide
10: dimethylformamide
11: 1.) n-BuLi, 3.) Na(Hg), MeOH / 1.) THF
12: n-Bu4NF
13: Ph3P
14: p-TsOH / tetrahydrofuran; H2O
15: 1.) MsCl, Py, DMAP, 2.) K2CO3 / 2.) MeOH
With
pyridine; methanol; dmap; sodium hydroxide; sodium tetrahydroborate; sodium periodate; n-butyllithium; 2,4-Dinitrophenol; sodium amalgam; zinc(II) tetrahydroborate; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; potassium carbonate; toluene-4-sulfonic acid; methanesulfonyl chloride; triphenylphosphine; lithium iodide; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; toluene;
DOI:10.1246/cl.1996.809
- Guidance literature:
-
Multi-step reaction with 10 steps
1: Et3N
2: K2CO3 / methanol
3: imidazole / dimethylformamide
4: HCOOH / diethyl ether
5: DEAD, Ph3P, LiCl
6: 1.) n-BuLi, 3.) Na(Hg), MeOH / 1.) THF
7: n-Bu4NF
8: Ph3P
9: p-TsOH / tetrahydrofuran; H2O
10: 1.) MsCl, Py, DMAP, 2.) K2CO3 / 2.) MeOH
With
pyridine; 1H-imidazole; methanol; dmap; n-butyllithium; formic acid; sodium amalgam; tetrabutyl ammonium fluoride; potassium carbonate; toluene-4-sulfonic acid; methanesulfonyl chloride; triethylamine; triphenylphosphine; lithium chloride; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; diethyl ether; water; N,N-dimethyl-formamide;
DOI:10.1246/cl.1996.809
- Guidance literature:
-
Multi-step reaction with 15 steps
1: 2,4-dinitrophenol / toluene / 140 °C
2: Zn(BH4)2
3: Py, DMAP
4: p-TsOH / tetrahydrofuran; H2O
5: NaIO4 / tetrahydrofuran; H2O
6: NaBH4 / methanol
7: 2M aq. NaOH
8: PPTS
9: DEAD, Ph3P, LiI / dimethylformamide
10: dimethylformamide
11: 1.) n-BuLi, 3.) Na(Hg), MeOH / 1.) THF
12: n-Bu4NF
13: Ph3P
14: p-TsOH / tetrahydrofuran; H2O
15: 1.) MsCl, Py, DMAP, 2.) K2CO3 / 2.) MeOH
With
pyridine; methanol; dmap; sodium hydroxide; sodium tetrahydroborate; sodium periodate; n-butyllithium; 2,4-Dinitrophenol; sodium amalgam; zinc(II) tetrahydroborate; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; potassium carbonate; toluene-4-sulfonic acid; methanesulfonyl chloride; triphenylphosphine; lithium iodide; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; toluene;
DOI:10.1246/cl.1996.809
