C₁₈H₁₇NSO₂

Base Information

• Chemical Name: C₁₈H₁₇NSO₂
• CAS No.: 947513-35-1
• Molecular Formula: C₁₈H₁₇NO₂S
• Molecular Weight: 311.404
• Mol file: 947513-35-1.mol

Synonyms:

Chemical Property of C₁₈H₁₇NSO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₁₇NSO₂

There total 5 articles about C₁₈H₁₇NSO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzo[b]thiophene-2,6-dicarboxylic acid 2-ethyl ester (850074-43-0) → C18H17NSO2 (947513-35-1)

Guidance literature:

Multi-step reaction with 3 steps

1: BH₃ / tetrahydrofuran

2: MnO₂ / CH₂Cl₂

3: NaBH(OAc)3 / 1,2-dichloro-ethane

With manganese(IV) oxide; borane; sodium tris(acetoxy)borohydride; In tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane;

DOI:10.1016/j.bmcl.2007.05.091

Reference yield:

6-hydroxymethyl-benzo[b]thiophene-2-carboxylic acid ethyl ester (850072-65-0) → C18H17NSO2 (947513-35-1)

Guidance literature:

Multi-step reaction with 2 steps

1: MnO₂ / CH₂Cl₂

2: NaBH(OAc)3 / 1,2-dichloro-ethane

With manganese(IV) oxide; sodium tris(acetoxy)borohydride; In dichloromethane; 1,2-dichloro-ethane;

DOI:10.1016/j.bmcl.2007.05.091

Reference yield:

2-ethyl 6-methyl benzo[b]thiophene-2,6-dicarboxylate (850074-42-9) → C18H17NSO2 (947513-35-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 53 percent / KI; pyridine / Heating

2: BH₃ / tetrahydrofuran

3: MnO₂ / CH₂Cl₂

4: NaBH(OAc)3 / 1,2-dichloro-ethane

With pyridine; manganese(IV) oxide; borane; sodium tris(acetoxy)borohydride; potassium iodide; In tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane;

DOI:10.1016/j.bmcl.2007.05.091

upstream raw materials:

6-formyI-benzo[b]thiophene-2-carboxylic acid ethyl ester

aniline

2-ethyl 6-methyl benzo[b]thiophene-2,6-dicarboxylate

benzo[b]thiophene-2,6-dicarboxylic acid 2-ethyl ester