Uridine, 2'-deoxy-5-(1-hydroxy-2-methoxyethyl)-

Base Information

Chemical Name:Uridine, 2'-deoxy-5-(1-hydroxy-2-methoxyethyl)-
CAS No.:123881-99-2
Molecular Formula:C₁₂H₁₈N₂O₇
Molecular Weight:302.284
Hs Code.:
DSSTox Substance ID:DTXSID90924625
Mol file:123881-99-2.mol

Synonyms:Uridine, 2'-deoxy-5-(1-hydroxy-2-methoxyethyl)-;123881-99-2;5-(1-Hydroxy-2-methoxyethyl)-2'-deoxyuridine;DTXSID90924625;5-(1,2-dihydroxyethyl)-2-deoxyuridine;1-(2-Deoxypentofuranosyl)-5-(1,2-dihydroxyethyl)-4-hydroxypyrimidin-2(1H)-one;5-(1,2-dihydroxyethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione

Suppliers and Price of Uridine, 2'-deoxy-5-(1-hydroxy-2-methoxyethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Uridine, 2'-deoxy-5-(1-hydroxy-2-methoxyethyl)-

Chemical Property:

XLogP3:-2.5
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:288.09575085
Heavy Atom Count:20
Complexity:439

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C(OC1N2C=C(C(=O)NC2=O)C(CO)O)CO)O
Isomeric SMILES:C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(CO)O)CO)O

Technology Process of Uridine, 2'-deoxy-5-(1-hydroxy-2-methoxyethyl)-

There total 3 articles about Uridine, 2'-deoxy-5-(1-hydroxy-2-methoxyethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 127911-91-5,123881-88-9
5-(1-hydroxy-2-iodoethyl)-2'-deoxyuridine

: 123882-01-9,123882-02-0
2,3-dihydro-3-hydroxy-5-(2'-deoxy-β-D-ribofuranosyl)furano<2,3-d>pyrimidin-6-(5H)-one

: 123881-99-2,123882-00-8
5-(1-hydroxy-2-methoxyethyl)-2'-deoxyuridine

Guidance literature:: With sodium carbonate; In methanol; at 25 ℃; for 6h;
DOI:10.1021/jm00164a039

Reference yield: 17.5%

: 67-56-1
methanol

: 127911-91-5,123881-88-9
5-(1-hydroxy-2-iodoethyl)-2'-deoxyuridine

: 123882-01-9,123882-02-0
2,3-dihydro-3-hydroxy-5-(2'-deoxy-β-D-ribofuranosyl)furano<2,3-d>pyrimidin-6-(5H)-one

: 123881-99-2,123882-00-8
5-(1-hydroxy-2-methoxyethyl)-2'-deoxyuridine

Guidance literature:: With sodium carbonate; at 25 ℃; for 6h;
DOI:10.1021/jm00164a039

Reference yield:

: 55520-67-7
5-vinyl-2'-deoxyuridine

: 123881-99-2,123882-00-8
5-(1-hydroxy-2-methoxyethyl)-2'-deoxyuridine

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / I₂, KIO₃, 5 N H₂SO₄ / H₂O; acetonitrile / 2 h / 55 °C

2: 26 percent / Na₂CO₃ / 6 h / 25 °C

With potassium iodate; sulfuric acid; iodine; sodium carbonate; In water; acetonitrile;
DOI:10.1021/jm00164a039