Technology Process of C19H19NO3
There total 3 articles about C19H19NO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-methoxy-phenylamine; 4-methoxy-benzaldehyde;
In
dichloromethane;
at 20 ℃;
for 1h;
Molecular sieve;
Inert atmosphere;
danishefsky's diene;
With
tetrachlorosilane; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at -78 ℃;
for 4h;
Inert atmosphere;
With
trifluoroacetic acid;
In
dichloromethane;
at -78 ℃;
for 0.25h;
Inert atmosphere;
DOI:10.1055/s-0028-1087677
- Guidance literature:
-
danishefsky's diene; N-(4-methoxybenzylidene)-2-methoxybenzenamine;
With
tetrachlorosilane; Methyl p-tolyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at -78 ℃;
for 4h;
Inert atmosphere;
Molecular sieve;
With
trifluoroacetic acid;
In
dichloromethane;
at -78 ℃;
Inert atmosphere;
Molecular sieve;
DOI:10.1111/j.1747-0285.2011.01102.x
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dichloromethane / 1 h / 20 °C / Inert atmosphere; Molecular sieve
2.1: tetrachlorosilane; Methyl p-tolyl sulfoxide; N-ethyl-N,N-diisopropylamine / dichloromethane / 4 h / -78 °C / Inert atmosphere; Molecular sieve
2.2: -78 °C / Inert atmosphere; Molecular sieve
With
tetrachlorosilane; Methyl p-tolyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
2.1: Aza-Diels-Alder reaction;
DOI:10.1111/j.1747-0285.2011.01102.x
