(6Z)-3,7,11-trimethyldodeca-6,10-dienal

Base Information

• Chemical Name: (6Z)-3,7,11-trimethyldodeca-6,10-dienal
• CAS No.: 172376-82-8
• Molecular Formula: C₁₅H₂₆O
• Molecular Weight: 222.371
• Mol file: 172376-82-8.mol

Synonyms:

Chemical Property of (6Z)-3,7,11-trimethyldodeca-6,10-dienal

Chemical Property:

• Vapor Pressure: 0.000639mmHg at 25°C

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6Z)-3,7,11-trimethyldodeca-6,10-dienal

There total 43 articles about (6Z)-3,7,11-trimethyldodeca-6,10-dienal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(3R)-N,N-diethyl-3,7,11-trimethyldodeca-1,6E,10-trien-1-amine → (R)-2,3-dihydrofarnesal (172376-82-8)

Guidance literature:

With sulfuric acid; In water; toluene; for 0.166667h;

Reference yield: 65.0%

Farnesal (502-67-0) → (6E)-3,7,11-trimethyl-6,10-dodecadienal (51513-58-7,172376-82-8)

Guidance literature:

With tri-n-butyl-tin hydride; acetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In benzene; at 20 ℃; for 1h;

DOI:10.1016/j.farmac.2004.06.007

Reference yield: 49.0%

1-hydroxy-3,7,11-trimethyl-6,10-dodecadiene (37519-97-4) → (3S)-dihydrofarnesal (194934-66-2,172376-82-8) + (R)-2,3-dihydrofarnesal (172376-82-8)

Guidance literature:

1-hydroxy-3,7,11-trimethyl-6,10-dodecadiene; With 4-methylmorpholine N-oxide; In dichloromethane; acetonitrile; at 20 ℃; for 0.5h; Molecular sieve;

With tetrapropylammonium perruthennate; In dichloromethane; acetonitrile; at 20 ℃; for 2h; stereoselective reaction;

upstream raw materials:

farnesal

Farnesol

(1EZ,6E)-3,7,11-trimethyl-1-triethylsiloxydodeca-1,6,10-triene

Farnesal

Downstream raw materials:

methyl (S,E)-2,3-dihydrofarnesenoate

(3R)-(6E)-2,3-dihydrofarnesol