2-bromo-4-chloronicotinaldehyde

Base Information

Chemical Name:2-bromo-4-chloronicotinaldehyde
CAS No.:1289197-78-9
Molecular Formula:C₆H₃BrClNO
Molecular Weight:220.453
Hs Code.:2933399990
Mol file:1289197-78-9.mol

Synonyms:

Suppliers and Price of 2-bromo-4-chloronicotinaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
2-Bromo-4-chloropyridine-3-carboxaldehyde 97%
1g
$ 96.90

Crysdot
2-Bromo-4-chloronicotinaldehyde 95+%
5g
$ 375.00

Crysdot
2-Bromo-4-chloronicotinaldehyde 95+%
10g
$ 593.00

Chemenu
2-Bromo-4-chloronicotinaldehyde 95+%
1000g
$ 12880.00

Chemenu
2-Bromo-4-chloronicotinaldehyde 95+%
500g
$ 8280.00

American Custom Chemicals Corporation
2-BROMO-4-CHLOROPYRIDINE-3-CARBALDEHYDE 95.00%
5MG
$ 454.04

Ambeed
2-Bromo-4-chloronicotinaldehyde 95%
1g
$ 80.00

Ambeed
2-Bromo-4-chloronicotinaldehyde 97+%
1g
$ 80.00

Ambeed
2-Bromo-4-chloronicotinaldehyde 95%
250mg
$ 43.00

Ambeed
2-Bromo-4-chloronicotinaldehyde 97+%
250mg
$ 42.00

Total 11 raw suppliers

Chemical Property of 2-bromo-4-chloronicotinaldehyde

Chemical Property:

Melting Point:83-87°C
Boiling Point:283.2±35.0 °C(Predicted)
PKA:-1.17±0.10(Predicted)
Density:1.800±0.06 g/cm3(Predicted)
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

2-Bromo-4-chloropyridine-3-carboxaldehyde 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T,Xi
Statements: 25-36
Safety Statements: 26-45

MSDS Files:

Useful:

Technology Process of 2-bromo-4-chloronicotinaldehyde

There total 1 articles about 2-bromo-4-chloronicotinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 22918-01-0
2-bromo-4-chloropyridine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 1289197-78-9
2-bromo-4-chloropyridine-3-carboxaldehyde

Guidance literature:: 2-bromo-4-chloropyridine; With lithium diisopropyl amide; In tetrahydrofuran; at -70 ℃; for 1.5h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; at -70 ℃; for 2h;

Reference yield: 48.0%

: 1289197-78-9
2-bromo-4-chloropyridine-3-carboxaldehyde

: 1433990-58-9
4,4-dimethyl-7-thia-10,11-diazatricyclo[6.4.0.0^2,6]dodeca-1⁽⁸⁾,2⁽⁶⁾,11-trien-9-one

: 4-chloro-2-{4,4-dimethyl-9-oxo-7-thia-10,11-diazatricyclo[6.4.0.0^2,6]dodeca-1(8),2(6),11-trien-10-yl}pyridine-3-carbaldehyde

Guidance literature:: With sarcosine; potassium carbonate; copper(I) bromide; at 95 ℃; for 15h;

Reference yield:

: 1289197-78-9
2-bromo-4-chloropyridine-3-carboxaldehyde

: 1433859-79-0
dibenzyl (2-(6-tert-Butyl-8-fluoro-1-oxophthalazin-2(1H)-yl)-4-(1-methyl-5-(5-methylisoxazol-3-ylamino)-6-oxo-1,6-dihydropyridin-3-yl)pyridin-3-yl)methyl phosphite

Guidance literature:: Multi-step reaction with 4 steps

1: potassium acetate; 4,7-dimethoxy-1,10-phenanthroline; copper(l) iodide / 1,4-dioxane / 10 h / 90 °C / Inert atmosphere

2: caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tricyclohexylphosphine / water; 1,4-dioxane / 3 h / Inert atmosphere; Reflux

3: methanol; sodium tetrahydroborate / 6 h / 20 °C

4: 1H-tetrazole / acetonitrile / 1 h / 20 °C

With 1H-tetrazole; methanol; sodium tetrahydroborate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; copper(l) iodide; 4,7-dimethoxy-1,10-phenanthroline; potassium acetate; caesium carbonate; tricyclohexylphosphine; In 1,4-dioxane; water; acetonitrile;