N-(2,4-dibromo-5-methylphenyl)acetamide

Base Information

• Chemical Name: N-(2,4-dibromo-5-methylphenyl)acetamide
• CAS No.: 36789-29-4
• Molecular Formula: C9H9 Br2 N O
• Molecular Weight: 306.985
• NSC Number: 139714
• DSSTox Substance ID: DTXSID70958004
• Wikidata: Q82938508
• Mol file: 36789-29-4.mol

Synonyms:36789-29-4;NSC139714;SCHEMBL2319917;DTXSID70958004;NSC-139714;N-(2,4-Dibromo-5-methylphenyl)ethanimidic acid

Chemical Property of N-(2,4-dibromo-5-methylphenyl)acetamide

Chemical Property:

• Vapor Pressure: 3.44E-06mmHg at 25°C
• Boiling Point: 386.8°C at 760 mmHg
• Flash Point: 187.8°C
• Density: 1.793g/cm³
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 306.90304
• Heavy Atom Count: 13
• Complexity: 198

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1Br)Br)NC(=O)C

Technology Process of N-(2,4-dibromo-5-methylphenyl)acetamide

There total 17 articles about N-(2,4-dibromo-5-methylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-Methylacetanilide (537-92-8) → N-(2,4-dibromo-5-methylphenyl)acetamide (36789-29-4)

Guidance literature:

With bromine; at 20 - 70 ℃; for 15h;

DOI:10.1016/j.ejmech.2018.06.059

Reference yield: 78.0%

3-Methylacetanilide (537-92-8) → 4-bromo-3-methylacetanilide (90914-81-1) + N-(2,4-dibromo-5-methylphenyl)acetamide (36789-29-4)

Guidance literature:

With copper diacetate; palladium diacetate; copper(ll) bromide; at 120 ℃; for 1h; neat (no solvent);

DOI:10.1039/c003074k

Reference yield: 78.0%

N-(2-bromophenyl)-2,2-dimethylpropanamide (65854-92-4) → 4-bromo-3-methylacetanilide (90914-81-1) + N-(2,4-dibromo-5-methylphenyl)acetamide (36789-29-4)

Guidance literature:

With copper diacetate; palladium diacetate; copper(ll) bromide; at 120 ℃; Neat (no solvent);

DOI:10.1039/c0dt00385a

upstream raw materials:

4-bromo-3-methylacetanilide

2,4-dibromo-5-methylaniline

acetic anhydride

C₁₀H₁₂BrNO₂S

Downstream raw materials:

2,4-dibromo-5-methylaniline

2,4-dibromo-5-methylphenol

2,4-dibromo-5-sulfamoylbenzoic acid