(R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester

Base Information

• Chemical Name: (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester
• CAS No.: 1372256-52-4
• Molecular Formula: C₁₂H₂₄N₂O₄
• Molecular Weight: 260.334
• Mol file: 1372256-52-4.mol

Synonyms:

Chemical Property of (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester

There total 21 articles about (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Nα-(benzyloxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine methyl ester (2389-49-3) → (S)-methyl 2-amino-6-(tert-butoxycarbonylamino)hexanoate (3017-32-1,1372256-52-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 4h; under 760 Torr;

DOI:10.1021/jo00233a006

Reference yield: 100.0%

C27H34N2O6 (172846-57-0) → (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester (63328-49-4,1372256-52-4)

Guidance literature:

With piperidine; In acetonitrile; at 20 ℃; for 3h;

DOI:10.1016/j.ejmech.2011.06.024

Reference yield: 100.0%

methyl (2R)-2-[[(benzyloxy)carbonyl]amino]-6-[[(tert-butoxy)carbonyl]amino]hexanoate (84559-78-4) → (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester (63328-49-4,1372256-52-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 4h; under 760 Torr;

DOI:10.1021/jo00233a006

upstream raw materials:

N^α-(benzyloxycarbonyl)-N^ε-(tert-butoxycarbonyl)-L-lysine methyl ester

Psoc-Lys(Boc)-OMe

methyl N²-(((9H-fluoren-9-yl)methoxy)carbonyl)-N⁶-(tert-butoxycarbonyl)-L-lysinate

Z-Lys(Boc)-OH

Downstream raw materials:

(S)-2-((R)-1-Benzyloxycarbonyl-ethylamino)-6-tert-butoxycarbonylamino-hexanoic acid methyl ester

N-Z-L-Seryl-N^ε-BOC-L-lysinmethylester

Z-Val-Lys(Boc)-O-Me

2-(4-benzyloxy-benzylamino)-6-tert-butoxycarbonylamino-hexanoic acid methyl ester