(4-((4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)methyl)benzyl)triphenylphosphonium acetate

Base Information

• Chemical Name: (4-((4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)methyl)benzyl)triphenylphosphonium acetate
• CAS No.: 1027312-69-1
• Molecular Formula: C₂H₃O₂*C₃₈H₄₆N₄O₄P
• Molecular Weight: 712.826
• Mol file: 1027312-69-1.mol

Synonyms:

Chemical Property of (4-((4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)methyl)benzyl)triphenylphosphonium acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-((4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)methyl)benzyl)triphenylphosphonium acetate

There total 1 articles about (4-((4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)methyl)benzyl)triphenylphosphonium acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

TPP-xy-Br + acetic acid (64-19-7,77671-22-8) + (7-tert-butoxycarbonylmethyl-1,4,7,10-tetraaza-cyclododec-1-yl)-acetic acid tert-butyl ester (162148-48-3) → (4-((4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl)methyl)benzyl)triphenylphosphonium acetate (1027312-69-1) + (4,4'-(4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecane-1,7-diyl)bis(methylene)bis(4,1-phenylene))bis(methylene)bis(triphenylphosphonium) bisacetate

Guidance literature:

TPP-xy-Br; (7-tert-butoxycarbonylmethyl-1,4,7,10-tetraaza-cyclododec-1-yl)-acetic acid tert-butyl ester; With triethylamine; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In water; at 20 ℃;

acetic acid; In water; N,N-dimethyl-formamide;

DOI:10.1021/jm7015045

upstream raw materials:

acetic acid

(7-tert-butoxycarbonylmethyl-1,4,7,10-tetraaza-cyclododec-1-yl)-acetic acid tert-butyl ester